Evidence map›Paper›PMID 30532993›Full record

ArticleJournal of global oncology2018

Factors Related to Advanced Stage of Cancer Presentation in Botswana.

Chidinma Anakwenze, Rohini Bhatia, William Rate, Lame Bakwenabatsile, Kebatshabile Ngoni, Sarah Rayne, Preet Dhillon, Mohan Narasimhamurthy, Ari Ho-Foster, Doreen Ramogola-Masire and 1 more

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In one paragraph

Article in Journal of global oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chidinma AnakwenzeChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Rohini BhatiaChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
William RateChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Lame BakwenabatsileChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Kebatshabile NgoniChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Sarah RayneChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Preet DhillonChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Mohan NarasimhamurthyChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Ari Ho-FosterChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Doreen Ramogola-MasireChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.
Surbhi GroverChidinma Anakwenze, MD Anderson Cancer Center, Houston, TX; Rohini Bhatia, University of Rochester School of Medicine and Dentistry, Rochester, NY; William Rate, Georgetown University School of Medicine, Washington, DC; Lame Bakwenabatsile, Ari Ho-Foster, and Surbhi Grover, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, and Philadelphia, PA; Kebatshabile Ngoni, Mohan Narasimhamurthy, and Doreen Ramogola-Masire, University of Botswana; Surbhi Grover, Princess Marina Hospital, Gaborone, Botswana; Sarah Rayne, University of the Witwatersrand, Johannesburg, South Africa; Preet Dhillon, Public Health Foundation of India, Gurgaon, Haryana, India; and Ari Ho-Foster, Doreen Ramogola-Masire and Surbhi Grover, University of Pennsylvania, Philadelphia, PA.

Funding

Shared Resources CoreU54CA190158 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ROBERTSON, ERLE S. · 2014 to 2023
$4.2M
NCI NIH HHS U54 CA190158
6 · The paper itself

Abstract

purposeBotswana, a country with a high prevalence of HIV, has an increasing incidence of cancer-related mortality in the post-antiretroviral therapy era. Despite universal access to free health care, the majority of Botswana patients with cancer present at advanced stages. This study was designed to explore the factors related to advanced-stage cancer presentation in Botswana.

methodsPatients attending an oncology clinic between December 2015 and January 2017 at Princess Marina Hospital in Gaborone, Botswana, completed a questionnaire on sociodemographic and clinical factors as well as cancer-related fears, attitudes, beliefs, and stigma. Odds ratios (ORs) were calculated to identify factors significantly associated with advanced stage (stage III and IV) at diagnosis.

resultsOf 214 patients, 18.7% were men and 81.3% were women. The median age at diagnosis was 46 years, with 71.9% of patients older than 40 years. The most commonly represented cancers included cervical (42.3%), breast (16%), and head and neck (15.5%). Cancer stages represented in the study group included 8.4% at stage I, 19.2% at stage II, 24.1% at stage III, 11.9% at stage IV, and 36.4% at an unknown stage. Patients who presented at advanced stages were significantly more likely to not be afraid of having cancer (OR, 3.48; P < .05), believe that their family would not care for them if they needed treatment (OR, 6.35; P = .05), and believe that they could not afford to develop cancer (OR, 2.73; P < .05). The perception that symptoms were less serious was also significantly related to advanced stage ( P < .05). Patients with non-female-specific cancers were more likely to present in advanced stages (OR, 5.67; P < .05).

conclusionFuture cancer mortality reduction efforts should emphasize cancer symptom awareness and early detection through routine cancer screening, as well as increasing the acceptability of care-seeking, especially among male patients.

Indexed as

BotswanaFemaleHumansMaleMiddle AgedNeoplasmsNeoplasm Staging

Identifiers

PMID30532993
PMCPMC6818282

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.