Evidence map›Paper›PMID 30532794›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Regulation Effect of a Chinese Herbal Formula on Flora and Mucosal Immune Secretory Immunoglobulin A in Rats.

Tian-Hao Liu, Xiao-Mei Zhang, Ni-Ping Han, Yang Liu, Yue-Ying Wu, Xiao-Ya Li, Zhong-Shan Yang, Jia-Li Yuan

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Repairing gut barrier by traditional Chinese medicine: roles of gut microbiota.Frontiers in cellular and infection microbiology · 2024
    Review
  2. Article
  3. Review
  4. Review
  5. Icariin Inhibits Intestinal Inflammation of DSS-Induced Colitis Mice Through Modulating Intestinal Flora Abundance and Modulating p-p65/p65 Molecule.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tian-Hao LiuSchool of Basic Medical Sciences, Yunnan University of Traditional Chinese Medicine, Yuhua Road, No. 1024, Kunming, Yunnan 650500, China.
Xiao-Mei ZhangSchool of Basic Medical Sciences, Yunnan University of Traditional Chinese Medicine, Yuhua Road, No. 1024, Kunming, Yunnan 650500, China.
Ni-Ping HanSchool of Basic Medical Sciences, Yunnan University of Traditional Chinese Medicine, Yuhua Road, No. 1024, Kunming, Yunnan 650500, China.
Yang LiuSchool of Basic Medical Sciences, Yunnan University of Traditional Chinese Medicine, Yuhua Road, No. 1024, Kunming, Yunnan 650500, China.
Yue-Ying WuSchool of Basic Medical Sciences, Yunnan University of Traditional Chinese Medicine, Yuhua Road, No. 1024, Kunming, Yunnan 650500, China.
Xiao-Ya LiSchool of Basic Medical Sciences, Yunnan University of Traditional Chinese Medicine, Yuhua Road, No. 1024, Kunming, Yunnan 650500, China.
Zhong-Shan YangSchool of Basic Medical Sciences, Yunnan University of Traditional Chinese Medicine, Yuhua Road, No. 1024, Kunming, Yunnan 650500, China.ORCID 0000-0002-5270-0119
Jia-Li YuanSchool of Basic Medical Sciences, Yunnan University of Traditional Chinese Medicine, Yuhua Road, No. 1024, Kunming, Yunnan 650500, China.ORCID 0000-0003-2236-0827
Yunnan University of Traditional Chinese Medicine · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flora and mucosal immunity are considered to be the barrier, which is associated with multiple respiratory diseases, including recurrent respiratory tract infection (RRTI). Fei-Xi-Tiao-Zhi-Fang (FTF) is a traditional Chinese herbal formula used in the treatment of RRTI. However, the mechanism is little known. This study aims to identify the function of FTF in flora and mucosal immune secretory immunoglobulin A (sIgA) in the model of RRTI rats. The samples of intestine and lung were collected to detect sIgA, short chain fatty acids (SCFAS), and flora with enzyme-linked immunosorbent assay (ELISA), gas chromatography, and 16S rDNA sequencing. The body weight and viscera index were increased dynamically in RRTI rats after the administration of FTF. Furthermore, the types and proportions of aboriginal flora were significantly changed in the model group, whereas the altered flora was rescued in the FTF administration group.

Identifiers

PMID30532794
PMCPMC6250008
OpenAlexW2900277667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.