Evidence map›Paper›PMID 30532793›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

The Impact of Previous Pregnancy Loss on Lactating Behaviors and Use of Herbal Medicines during Breastfeeding: A Post Hoc Analysis of the Herbal Supplements in Breastfeeding InvesTigation (HaBIT).

Alessandra Bettiol, Niccolò Lombardi, Ettore Marconi, Giada Crescioli, Roberto Bonaiuti, Valentina Maggini, Eugenia Gallo, Alessandro Mugelli, Fabio Firenzuoli, Claudia Ravaldi and 1 more

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessandra BettiolDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Niccolò LombardiDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Ettore MarconiDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Giada CrescioliDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Roberto BonaiutiDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Valentina MagginiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID 0000-0002-4227-7214
Eugenia GalloDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID 0000-0003-3025-1698
Alessandro MugelliDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.
Fabio FirenzuoliCenter for Integrative Medicine, Careggi University Hospital, University of Florence, Florence, Italy.ORCID 0000-0003-1911-2021
Claudia RavaldiCiaoLapo Onlus, Charity for Healthy Pregnancy, Stillbirth and Perinatal Loss Support, Prato, Italy.
Alfredo VannacciDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Tuscan Regional Centre of Pharmacovigilance and Phytovigilance, Florence, Italy.ORCID 0000-0001-5259-2026

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionComplementary and alternative medicines (CAMs) are commonly used among lactating women, despite the poor knowledge of these products and of their safety. Perception of pregnancy- and breastfeeding-related difficulties and consequent use of CAMs may differ in bereaved women, by force of the distress related to previous loss, although no literature evidence is available. This Herbal supplements in Breastfeeding InvesTigation (HaBIT) post hoc analysis explored the impact of previous pregnancy loss on lactating behaviors and on use of CAMs during breastfeeding.

methodsA web-based survey was conducted among lactating women with no previous alive child, resident in Tuscany (Italy). Data on lactating behavior and on CAMs use were collected and evaluated among women with previous pregnancy loss as compared to control women.

resultsOut of 476 women answering the questionnaire, 233 lactating women with one child were considered. Of them, 80 had history of pregnancy loss. Cesarean birth was significantly more frequent among women with history of pregnancy loss as compared to controls (41% versus 22%;

conclusionOvercoming the social taboo of pregnancy loss and training healthcare professionals for an adequate management of the perinatal period are essential for an effective and safe care. Despite the common use and advice on CAMs use during breastfeeding, it is important to acknowledge that limited evidence supports their safety and efficacy during such critical period.

Identifiers

PMID30532793
PMCPMC6250025

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.