Evidence map›Paper›PMID 30532684›Full record

ReviewEJIFCC2000

Criteria for specific measurement of plasminogen (enzymatic; procedure) in human plasma.

Johannes J Sidelmann, Nuala A Booth, Johannes Hoffmann, Michael E Nesheim, Steffen Rosén

Open access · greenAbstract readReview
In one paragraph

Review in EJIFCC, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Johannes J SidelmannDepartment for Thrombosis Research, University of Southern Denmark, Esbjerg, Denmark.
Nuala A BoothDepartment of Molecular & Cell Biology, Institute of Medical Sciences, University of Aberdeen, Scotland.
Johannes HoffmannClinical Laboratories, Catharina Hospital, Eindhoven, the Netherlands.
Michael E NesheimDepartment of Biochemistry, Queens University, Kingston, Ontario, Canada.
Steffen RosénChromogenix AB, Mölndal, Sweden.
ChromoGenics (Sweden) · SEQueen's University · CAUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a lack of well-established criteria for the specific measurement of fibrinolytic variables. On behalf of the SSC the Subcommittee on Fibrinolysis started a process to develop such criteria. This report describes the criteria for the measurement of plasminogen (enzymatic; procedure) in human plasma. Apparently, the most specific methods for determination of plasminogen (enzymatic; procedure) adhere to the principle of streptokinase induced activation of plasminogen and recording of activity using a chromogenic substrate. Incorporation of fibrinogen attenuates the potential effect of elevated fibrinogen or fibrin(ogen) fragments in the plasma sample. The criteria for specific measurement of plasminogen(enzymatic; procedure) are based on this analytical principle. The kinetics and principles of the assay procedure are described, and criteria as well as test methods for criteria are detailed. Guidelines for standardization, quality assurance, analytical sensitivity and establishment of reference intervals are given. The pre-analytical conditions regarding preparation of the patient and the specimen are delineated. Nonstandard abbreviations: SSC, Scientific and Standardization Committee; ISTH, The International Society on Thrombosis and Haemostasis; IFCC, The International Federation of Clinical Chemistry; NCCLS, National Center for Clinical Laboratory Standards; HRG, histidine-rich glycoprotein; Lp(a), lipoprotein (a); SK, streptokinase.

Identifiers

PMID30532684
PMCPMC6282604
OpenAlexW2781564085

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.