Evidence map›Paper›PMID 30532598›Full record

ArticleClinical epidemiology2018

Thirty-year trends in dementia: a nationwide population study of Swedish inpatient records.

Dominika Seblova, Maria Lopez Quiroga, Stefan Fors, Kristina Johnell, Martin Lövdén, Antonio Ponce de Leon, Anna Christina Svensson, Susanne Wicks, Anton Lager

Abstract read
In one paragraph

Article in Clinical epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Is Alzheimer disease a disease?Nature reviews. Neurology · 2024
    Review
  8. Review
  9. Decreasing Incidence and Prevalence of Dementia Among Octogenarians: A Population-Based Study on 3 Cohorts Born 30 Years Apart.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. [Diagnosis and treatment of vascular dementia].Zeitschrift fur Gerontologie und Geriatrie · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dominika SeblovaAging Research Center, Karolinska Institutet, Stockholm, Sweden, dominika.seblova@ki.se.
Maria Lopez QuirogaComplutense University of Madrid, Madrid, Spain.
Stefan ForsAging Research Center, Karolinska Institutet, Stockholm, Sweden, dominika.seblova@ki.se.
Kristina JohnellAging Research Center, Karolinska Institutet, Stockholm, Sweden, dominika.seblova@ki.se.
Martin LövdénAging Research Center, Karolinska Institutet, Stockholm, Sweden, dominika.seblova@ki.se.
Antonio Ponce de LeonDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden, dominika.seblova@ki.se.
Anna Christina SvenssonDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden, dominika.seblova@ki.se.
Susanne WicksDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden, dominika.seblova@ki.se.
Anton LagerAging Research Center, Karolinska Institutet, Stockholm, Sweden, dominika.seblova@ki.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe continuous growth of the current dementia epidemic is contingent on the stability of age- and sex-specific trends over time. However, recent evidence suggests declining or stable trends. The aim of this study was to evaluate the real-world changes in the burden of dementia in older adults in Sweden from 1987 to 2016 by estimating age- and sex-specific incidence of dementia diagnosis in hospital inpatient records (dementia incidence). Differences in trends by sex, age, and educational levels were also examined.

methodsThe entire Swedish population aged 65 years and older was followed up from 1987 to 2016. Age-, sex-, and education-stratified dementia incidence rates for every follow-up year were estimated using the National Patient Register. Hazard ratio of receiving a dementia diagnosis in the inpatient records per 1 calendar year increase was estimated with discrete time logistic models with a complementary log-log link.

resultsAfter increase, especially in those >85 years of age, dementia incidence started to decrease in the last 5 years of the study period. After 2011, 1 calendar year increase was associated with lower hazard ratio of receiving a hospital diagnosis of dementia. The decrease had the highest magnitude in 70-74-year-olds (-5.5%), followed by 75-79-year-olds (-4.5%) and 80-84-year-olds (-4.0%). The decrease was present in both sexes and at all educational levels up to 90 years of age. Age was associated with the level of dementia incidence, and the trends differed by age group. Educational gradient was observed. University-educated older adults had the lowest rates of dementia. However, the trend over time did not substantially differ by sex or educational level.

conclusionOur results provide more evidence that dementia incidence may be declining. They also suggest that at least in hospitals, the number of new patients with dementia may decrease in the future.

Indexed as

Alzheimer’seducationheterogeneous associationhospitalizationincidencepopulation study

Identifiers

PMID30532598
PMCPMC6247947

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.