Evidence map›Paper›PMID 30532549›Full record

ArticleTherapeutics and clinical risk management2018

Perceptions of heart failure symptoms, disease severity, treatment decision-making, and side effects by patients and cardiologists: a multinational survey in a cardiology setting.

Sara Bruce Wirta, Bogdan Balas, Catia C Proenca, Hollie Bailey, Zoe Phillips, James Jackson, Sarah Cotton

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
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  5. Clinical Decision-Making for Heart Failure in Kosovo: A Conjoint Analysis.International journal of environmental research and public health · 2022
    Article
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  7. Mechanism of Dyspnea during Exercise in Children with Corrected Congenital Heart Disease.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Sara Bruce WirtaReal World Evidence, Cardio-Metabolic Franchise, Novartis Sweden, Stockholm, Sweden.
Bogdan BalasReal World Evidence, Cardio-Metabolic Franchise, Novartis Pharma, Basel, Switzerland.
Catia C ProencaWellmera AG, Basel, Switzerland.
Hollie BaileyReal World Research, Adelphi Real World, Bollington, UK, james.jackson@adelphigroup.com.
Zoe PhillipsReal World Research, Adelphi Real World, Bollington, UK, james.jackson@adelphigroup.com.
James JacksonReal World Research, Adelphi Real World, Bollington, UK, james.jackson@adelphigroup.com.
Sarah CottonReal World Research, Adelphi Real World, Bollington, UK, james.jackson@adelphigroup.com.
Adelphi Group (United Kingdom) · GBNovartis (Sweden) · SENovartis (Switzerland) · CHSanthera Pharmaceuticals (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeExplore the extent to which heart failure (HF) symptoms and side effects of HF treatment experienced by patients are recognized by cardiologists, and concordance between patient-cardiologist perceptions of HF severity and patients' contributions to treatment decision-making.

methodsA multinational, cross-sectional survey of cardiologists and patients with HF was conducted. Patient-record forms (PRFs) were completed by cardiologists for consecutive consulting patients with HF, who completed a patient self-completion questionnaire (PSC). Responses from PRFs with an associated PSC were analyzed to compare patient- and cardiologist-reported occurrences of HF symptoms and treatment side effects, patient-perceived severity of HF and cardiologists' perceived risk of death within 12 months, and patient input into treatment decisions. Concordance was calculated as the number of response agreements between PSCs and PRFs for total number of matched pairs. Over- or underreporting of symptoms and side effects by cardiologists relative to patient-reported occurrences were calculated.

resultsOverall, 2,454 patient-cardiologist pairs were identified. High levels of concordance between matched pairs were observed for the occurrence of reported HF symptoms (93%), side effects (77%-98%) and degree of patient input into treatment decisions (74%); for perceived HF severity, concordance was 54%. Most symptoms (except dyspnea when active and fatigue/weakness, experienced by >50% of patients) were underreported by cardiologists. Of patients reporting to have been informed by their cardiologist that their HF was mild, 28% were perceived by their cardiologist to have a moderate-high/very high risk of death within 12 months. Treatment choice was not discussed with almost a third of patients. When discussed, 94% of patients (n=1,540) reported the cardiologist made the final decision. Cardiologists more often under- than overreported the occurrence of side effects reported by patients.

conclusionImproved patient-cardiologist dialogue and shared decision-making is required for optimizing patient care and outcomes in HF.

Indexed as

disease awarenessdisease-specific programpatient influencepatient-reported outcomesreal worldtreatment decision-making

Identifiers

PMID30532549
PMCPMC6247946
OpenAlexW2901693829

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.