ArticleNeuropsychiatric disease and treatment2018
Aberrant prefrontal-parietal-cerebellar circuits in alcohol dependence.
Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Systematic review on resting-state fMRI in people with AUD and people who binge drink.Molecular psychiatry · 2025Pooled it
- The resting-state brain activity signatures for addictive disorders.Med (New York, N.Y.) · 2024Pooled it
- Fractal Analysis of Brain Activity During Risky Drinking in Adolescents and Young Adults.Brain sciences · 2025Article
- Changes in resting-state brain function in chronic alcohol users based on degree centrality.The Journal of international medical research · 2025Article
- Insula under the influence: Alcohol-induced changes in resting state functional connectivity.Alcohol, clinical & experimental research · 2025Article
- Brain functional alterations in early stage of coal workers' pneumoconiosis with alcoholism: insights from a resting-state fMRI investigation.Frontiers in neuroscience · 2025Article
- A voxel-level resting-state fMRI study on patients with alcohol use disorders based on a power spectrum slope analysis method.Frontiers in neuroscience · 2024Article
- Alterations of brain activity in patients with alcohol use disorder: a resting-state fMRI study.BMC psychiatry · 2023Article
- Advances in neuroimaging studies of alcohol use disorder (AUD).Psychoradiology · 2022Review
- Aberrant intrinsic neural network strength in individuals with "smartphone addiction": An MRI data fusion study.Brain and behavior · 2022Article
- Alcohol-induced brain deficit in alcohol dependence.Frontiers in neurology · 2022Article
- Differential effects of alcohol-drinking patterns on the structure and function of the brain and cognitive performance in young adult drinkers: A pilot study.Brain and behavior · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify whether the amplitude of low-frequency fluctuations (ALFF) analysis has the potential to serve as a biological marker to detect alcohol-induced spontaneous brain activities and distinguish the patients with alcohol dependence from the healthy subjects.
methodsWe utilized the ALFF analysis to report on the alcohol-induced spontaneous brain activities in 29 patients with alcohol dependence (9 female, 20 male) relative to 29 status-matched healthy subjects (11 female, 18 male). Receiver operating characteristic curve was used to test the ability of the ALFF analysis in discriminating the patients with alcohol dependence from the healthy subjects. Pearson correlation was used to evaluate the relationships between the signal value of those ALFF differences in brain areas and behavioral characteristics.
resultsAlcohol-induced brain differences located in the right inferior parietal lobule and right supplementary motor area with significant higher ALFF values, and in the left precuneus and bilateral cerebellum posterior lobe with lower ALFF values. The movement-related areas were significantly correlated with each other (
conclusionThe ALFF analysis may serve as a biological indicator to detect the spontaneous brain activities in patients with alcohol dependence. The prefrontal-parietal-cerebellar circuit appears to be disturbed by long-term alcoholism in patients with alcohol dependence.
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