Evidence map›Paper›PMID 30532528›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease

Validation of clinical control in COPD as a new tool for optimizing treatment.

Juan José Soler-Cataluña, Maribel Marzo, Pablo Catalán, Cristina Miralles, Bernardino Alcazar, Marc Miravitlles

Abstract readObservational StudyValidation Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Real-Life Effectiveness of Aclidinium/Formoterol on COPD Control: The REDACT Observational Study.International journal of chronic obstructive pulmonary disease · 2026
    Observational
  8. Article
  9. Exploring Clinical Control of COPD: Insights From a Portuguese Outpatient Population.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025
    Article
  10. Article
  11. Is Disease Stability an Attainable Chronic Obstructive Pulmonary Disease Treatment Goal?American journal of respiratory and critical care medicine · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Future concepts in bronchodilation for COPD: dual-European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juan José Soler-CataluñaPneumology Department, Hospital Arnau de Vilanova, Valencia, Spain.
Maribel MarzoEmergency Department, Hospital General de Requena, Valencia, Spain.
Pablo CatalánPneumology Department, Hospital Arnau de Vilanova, Valencia, Spain.
Cristina MirallesPneumology Department, Hospital Arnau de Vilanova, Valencia, Spain.
Bernardino AlcazarCIBER of Respiratory Diseases (CIBERES), Spain, mmiravitlles@vhebron.net.
Marc MiravitllesCIBER of Respiratory Diseases (CIBERES), Spain, mmiravitlles@vhebron.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has recently been proposed that the concept of clinical control in COPD may be useful for deciding treatment in COPD, but the original control criteria (OCC) were considered too restrictive.

objectiveDefine and subsequently validate "modified" control criteria (MCC) of COPD.

methodProspective observational study in COPD patients with a 1-year follow-up. Control was defined as the presence of low clinical impact and clinical stability. To evaluate clinical impact, the following clinical parameters were assessed: the degree of dyspnea, use of rescue medication, physical activity, and sputum color. Stability was assessed by clinical changes and exacerbations in the last 3 months. The COPD assessment test score and their changes were also evaluated as alternative control criteria. To define the MCC, adjustment for disease severity using BODEx index (MCC-B) or FEV

resultsWe included 265 patients, 224 (83.9%) men, with a mean age (±SD) of 68±9 years and FEV

conclusionsThe new MCC identified a higher number of controlled COPD patients. These patients have a better quality of life and lower risk of poor outcomes. The concept of control and the new MCC could be a useful tool to optimize therapy.

Indexed as

Decision Support TechniquesHealth Status IndicatorsAgedAged, 80 and overBronchodilator AgentsClinical Decision-MakingDisease ProgressionDyspneaExerciseExercise ToleranceFemaleForced Expiratory VolumeHealth StatusHospitalizationHumansLungBronchodilator AgentsCATcontrolCOPDoutcomes

Identifiers

PMID30532528
PMCPMC6241720

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.