Evidence map›Paper›PMID 30532277›Full record

ArticlePloS one2018

K-edge subtraction imaging for coronary angiography with a compact synchrotron X-ray source.

Stephanie Kulpe, Martin Dierolf, Eva Braig, Benedikt Günther, Klaus Achterhold, Bernhard Gleich, Julia Herzen, Ernst Rummeny, Franz Pfeiffer, Daniela Pfeiffer

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Stephanie KulpeChair of Biomedical Physics, Department of Physics, Technical University of Munich, Garching, Germany.ORCID 0000-0002-8102-3524
Martin DierolfChair of Biomedical Physics, Department of Physics, Technical University of Munich, Garching, Germany.ORCID 0000-0001-5150-2949
Eva BraigChair of Biomedical Physics, Department of Physics, Technical University of Munich, Garching, Germany.
Benedikt GüntherChair of Biomedical Physics, Department of Physics, Technical University of Munich, Garching, Germany.
Klaus AchterholdChair of Biomedical Physics, Department of Physics, Technical University of Munich, Garching, Germany.
Bernhard GleichMunich School of BioEngineering, Technical University of Munich, Garching, Germany.
Julia HerzenChair of Biomedical Physics, Department of Physics, Technical University of Munich, Garching, Germany.
Ernst RummenyDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Franz PfeifferChair of Biomedical Physics, Department of Physics, Technical University of Munich, Garching, Germany.
Daniela PfeifferDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Technical University of Munich · DETUM Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

About one third of all deaths worldwide can be traced back to cardiovascular diseases. An interventional radiology procedure for their diagnosis is Digital Subtraction Angiography (DSA). An alternative to DSA is K-Edge subtraction (KES) imaging, which has been shown to be advantageous for moving organs and eliminating image artifacts caused by patient movement. As highly brilliant, monochromatic X-rays are required for this method, it has been limited to synchrotron facilities so far, restraining the feasibility in clinical routine. Compact synchrotron X-ray sources based on inverse Compton scattering, which have been evolving substantially over the past decade, provide X-rays with sufficient brilliance that meet spatial and financial requirements affordable in laboratory settings or for university hospitals. In this work, we demonstrate a first proof-of-principle K-edge subtraction imaging experiment using the Munich Compact Light Source (MuCLS), the first user-dedicated installation of a compact synchrotron X-ray source worldwide. It is shown experimentally that the technique of KES increases the visibility of small blood vessels overlaid by bone structures.

Indexed as

Angiography, Digital SubtractionSynchrotronsX-RaysAnimalsCoronary AngiographyEquipment DesignFeasibility StudiesHeartImage Processing, Computer-AssistedPhantoms, ImagingRadiographic Image EnhancementRib CageSignal-To-Noise RatioSwine

Identifiers

PMID30532277
PMCPMC6287837
OpenAlexW2904889716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.