ArticlePloS one2018
Beyond confidence: Development of a measure assessing the 5C psychological antecedents of vaccination.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07721649 (Intrahospital Vaccination and Active Counseling Versus Active Counseling Alone to Increase Seasonal Influenza immUnization in Patients at High Cardiovascular Risk in Germany), which is not on this map. Cited by 758 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intrahospital Vaccination and Active Counseling Versus Active Counseling Alone to Increase Seasonal Influenza immUnization in Patients at High Cardiovascular Risk in Germany: The Randomized Controlled VACC-UP Study
Who cites it
758 citing papers in PubMed, 4 syntheses or guidelines pooled it, 1,253 citations in OpenAlex.
- Tailoring educational interventions targeting parental vaccine hesitancy: a systematic review of quantitative studies.Frontiers in public health · 2026Pooled it
- Comparative synthesis of sociocultural and political influences (SPIs) on COVID-19 vaccine hesitancy: an interdisciplinary systematic review.BMC public health · 2025Pooled it
- Factors that influence caregivers' and adolescents' views and practices regarding human papillomavirus (HPV) vaccination for adolescents: a qualitative evidence synthesis.The Cochrane database of systematic reviews · 2025Pooled it
- Factors influencing vaccine hesitancy toward non-covid vaccines in South Asia: a systematic review.BMC public health · 2025Pooled it
- Codesigning COVID-19 booster promotion materials in online workshops with long-term care staff: a process evaluation.Health education research · 2026Trial
- Effects of debunking interventions on endorsement of alternative medicine: a randomized controlled experiment in Peru.Scientific reports · 2026Trial
- Effectiveness of a video-based intervention for COVID-19 vaccine acceptance among individuals with mental disorders: a randomized online experiment.Frontiers in public health · 2026Trial
- A randomized assessment of the impact of 'Those Nerdy Girls' newsletters on adult vaccination outcomes.PloS one · 2026Trial
- How to Improve People's Intentions Regarding COVID-19 Vaccination in China: A Randomized Controlled Trial.International journal of behavioral medicine · 2025Trial
- Using an inferior decoy alternative to nudge COVID-19 vaccination.Scientific reports · 2025Trial
- Heterogeneity in the psychological antecedents of influenza vaccination among Chinese older adults: A 5C model approach.Human vaccines & immunotherapeutics · 2026Article
- 5C psychological antecedents of vaccine hesitancy toward maternal RSV vaccines and infant monoclonal antibodies among pregnant and postpartum women and their partners in China: A multicenter, dyadic survey design, cross-sectional study.Human vaccines & immunotherapeutics · 2026Article
- What shapes influenza attitudes and behaviors in Italy? Insights from a cross-sectional study.Human vaccines & immunotherapeutics · 2026Article
- Validation of the behavioural and social drivers of influenza vaccine survey in Australia: Cognitive interviews and psychometric evaluation.Human vaccines & immunotherapeutics · 2026Article
- Bridging the intention‒behavior gap in herpes zoster vaccination: A nationwide survey in a self-payment setting.Human vaccines & immunotherapeutics · 2026Article
- Occupational HPV exposure and vaccination among healthcare workers: Implications for institutional vaccination strategies.Human vaccines & immunotherapeutics · 2026Article
- The role of age, sex, and ethnicity in vaccine trust, and sources of information in Canada: Findings from a national survey.Human vaccines & immunotherapeutics · 2026Article
- Examining determinants of COVID-19 vaccine hesitancy and acceptance among Arab university students: A regional scoping review.Human vaccines & immunotherapeutics · 2026Article
- How the unvaccinated have been portrayed in the urban English-language Canadian popular press since the declared end of the COVID-19 pandemic emergency.Human vaccines & immunotherapeutics · 2026Article
- Vaccine literacy among Italian travelers: A web-based survey using a brief assessment tool.Human vaccines & immunotherapeutics · 2026Article
698 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMonitoring the reasons why a considerable number of people do not receive recommended vaccinations allows identification of important trends over time, and designing and evaluating strategies to address vaccine hesitancy and increase vaccine uptake. Existing validated measures assessing vaccine hesitancy focus primarily on confidence in vaccines and the system that delivers them. However, empirical and theoretical work has stated that complacency (not perceiving diseases as high risk), constraints (structural and psychological barriers), calculation (engagement in extensive information searching), and aspects pertaining to collective responsibility (willingness to protect others) also play a role in explaining vaccination behavior. The objective was therefore to develop a validated measure of these 5C psychological antecedents of vaccination. METHODS AND
findingsThree cross-sectional studies were conducted. Study 1 uses factor analysis to develop an initial scale and assesses the sub-scales' convergent, discriminant, and concurrent validity (N = 1,445, two German convenience-samples). In Study 2, a sample representative regarding age and gender for the German population (N = 1,003) completed the measure for vaccination in general and for specific vaccinations to assess the potential need for a vaccine-specific wording of items. Study 3 compared the novel scale's performance with six existing measures of vaccine hesitancy (N = 350, US convenience-sample). As an outcome, a long (15-item) and short (5-item) 5C scale were developed as reliable and valid indicators of confidence, complacency, constraints, calculation, and collective responsibility. The 5C sub-scales correlated with relevant psychological concepts, such as attitude (confidence), perceived personal health status and invulnerability (complacency), self-control (constraints), preference for deliberation (calculation), and communal orientation (collective responsibility), among others. The new scale provided similar results when formulated in a general vs. vaccine-specific way (Study 2). In a comparison of seven measures the 5C scale was constantly among the scales that explained the highest amounts of variance in analyses predicting single vaccinations (between 20% and 40%; Study 3). The present studies are limited to the concurrent validity of the scales.
conclusionsThe 5C scale provides a novel tool to monitor psychological antecedents of vaccination and facilitates diagnosis, intervention design and evaluation. Its short version is suitable for field settings and regular global monitoring of relevant antecedents of vaccination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.