ArticlePloS one2018
Depressive symptoms as a barrier to engagement in physical activity in older adults with and without Alzheimer's disease.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 38 citations in OpenAlex.
- Impaired sleep, depressive symptoms, and pain as determinants of physical activity and exercise intervention adherence: an exploratory analysis of a randomized clinical trial.BMC geriatrics · 2025Trial
- The interplay of risk factors for future falls and fall-related injuries among community-dwelling older adults: a Bayesian network analysis.BMC public health · 2026Article
- Unveiling the Digital Phenotype of Physical Activity Behavior in Community-Dwelling Older Adults Using Machine Learning.Bioengineering (Basel, Switzerland) · 2026Article
- Tailored Personas for Lung Transplant Recipients' Return-to-Work Experiences: A Secondary Analysis of Qualitative Data.Patient preference and adherence · 2026Article
- Caring While Moving: Case Studies on Physical Activity and Dementia Caregiver Well-Being.Healthcare (Basel, Switzerland) · 2025Article
- Meaning in life: bidirectional relationship with depression, anxiety, and loneliness in a longitudinal cohort of older primary care patients with multimorbidity.BMC geriatrics · 2025Article
- Review
- Activity patterns are associated with fractional lifespan, memory, and gait speed in aged dogs.Scientific reports · 2023Article
- Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment.Psychiatry and clinical neurosciences · 2022Review
- Depressive Symptoms, Leisure Activity Engagement, and Global Cognition in Non-Hispanic Black and White Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Sex- and Neuropsychiatric-Dependent Circadian Alterations in Daily Voluntary Physical Activity Engagement and Patterns in Aged 3xTg-AD Mice.International journal of molecular sciences · 2022Article
- No travel worsens depression: reciprocal relationship between travel and depression among older adults.Annals of general psychiatry · 2022Article
- Fun and a meaningful routine: the experience of physical activity in people with dementia.BMC geriatrics · 2022Article
- The relationship between social participation and depressive symptoms among Chinese middle-aged and older adults: A cross-lagged panel analysis.Frontiers in public health · 2022Article
- Perceived Opportunities for Physical Activity and Willingness to Be More Active in Older Adults with Different Physical Activity Levels.International journal of environmental research and public health · 2021Article
- Influence of the Perception of Barriers in Practice of PA in Adolescents: Explanatory Model.Healthcare (Basel, Switzerland) · 2021Article
- Quality of Life and Caregiver Burden of Alzheimer's Disease Among Community Dwelling Patients in Europe: Variation by Disease Severity and Progression.Journal of Alzheimer's disease reports · 2021Article
- Ethnic Differences in Barriers and Enablers to Physical Activity Among Older Adults.Frontiers in public health · 2021Article
- Cross-sectional association between physical activity level and subjective cognitive decline among US adults aged ≥45 years, 2015.Preventive medicine · 2020Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesPhysical activity shows promise for reduced risk of Alzheimer's disease (AD) and protection against cognitive decline among individuals with and without AD. Older adults face many barriers to adoption of physically active lifestyles and people with AD face even further challenges. Physical activity is a promising non-pharmacological approach to improve depressive symptoms, but little is known about the impact of depressive symptoms as a potential barrier to engagement in physical activity. The present study aimed to investigate depressive symptoms as a potential barrier for participation in physical activity across a range of dementia severity.
methodWe used longitudinal structural equation modelling to investigate the bi-directional relationship between depressive symptoms and physical activity in 594 older adults with and without AD over a 2 year longitudinal follow up. Participants ranged from no cognitive impairment to moderately severe AD.
resultsWe found that depressive symptoms predicted reduced engagement in subsequent physical activity, but physical activity did not predict subsequent reductions in depressive symptoms.
conclusionWe conclude that depressive symptoms may be an important barrier to engagement in physical activity that may be addressed in clinical practice and intervention research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.