ArticlePLoS computational biology2018
Odorant mixtures elicit less variable and faster responses than pure odorants.
Article in PLoS computational biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Treatment of cotton with plant growth-promoting rhizobacteria consortium alters host location and oviposition of Spodoptera exigua.Pest management science · 2026Article
- CanInsects · 2026Article
- Microbial, proteomic, and metabolomic profiling of the estrous cycle in wild house mice.Microbiology spectrum · 2024Article
- Gain modulation and odor concentration invariance in early olfactory networks.PLoS computational biology · 2023Article
- Multielectrode recordings of cockroach antennal lobe neurons in response to temporal dynamics of odor concentrations.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Article
- Geosmin suppresses defensive behaviour and elicits unusual neural responses in honey bees.Scientific reports · 2023Article
- Hyperbolic odorant mixtures as a basis for more efficient signaling between flowering plants and bees.PloS one · 2022Article
- Non-synaptic interactions between olfactory receptor neurons, a possible key feature of odor processing in flies.PLoS computational biology · 2021Article
- Control of red flour beetle (Tribolium castaneum) in feeds and commercial poultry diets via using a blend of clove and lemongrass extracts.Environmental science and pollution research international · 2021Article
- Article
- Flying Drosophila show sex-specific attraction to fly-labelled food.Scientific reports · 2019Article
- Commercially Available Essential Oil Formulas as Repellents Against the Stored-Product PestInsects · 2019Article
- Odor Stimuli: Not Just Chemical Identity.Frontiers in physiology · 2019Review
- Insect Odorscapes: From Plant Volatiles to Natural Olfactory Scenes.Frontiers in physiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In natural environments, odors are typically mixtures of several different chemical compounds. However, the implications of mixtures for odor processing have not been fully investigated. We have extended a standard olfactory receptor model to mixtures and found through its mathematical analysis that odorant-evoked activity patterns are more stable across concentrations and first-spike latencies of receptor neurons are shorter for mixtures than for pure odorants. Shorter first-spike latencies arise from the nonlinear dependence of binding rate on odorant concentration, commonly described by the Hill coefficient, while the more stable activity patterns result from the competition between different ligands for receptor sites. These results are consistent with observations from numerical simulations and physiological recordings in the olfactory system of insects. Our results suggest that mixtures allow faster and more reliable olfactory coding, which could be one of the reasons why animals often use mixtures in chemical signaling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.