Evidence map›Paper›PMID 30532141›Full record

ArticlePloS one2018

Unwarranted regional variation in vertebroplasty and kyphoplasty in Switzerland: A population-based small area variation analysis.

Claudia Scheuter, Maria M Wertli, Alan G Haynes, Radoslaw Panczak, Arnaud Chiolero, Arnaud Perrier, Nicolas Rodondi, Drahomir Aujesky

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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  5. The Swiss health care atlas-relaunch in scale.Research in health services & regions · 2023
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  8. Trends and regional variation in vertebroplasty and kyphoplasty in Switzerland: a population-based small area analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Claudia ScheuterDivision of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.
Maria M WertliDivision of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.ORCID 0000-0001-6347-0198
Alan G HaynesClinical Trials Unit, University of Bern, Bern, Switzerland.
Radoslaw PanczakClinical Trials Unit, University of Bern, Bern, Switzerland.
Arnaud ChioleroInstitute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Arnaud PerrierDivision of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals, Geneva, Switzerland.
Nicolas RodondiDivision of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.
Drahomir AujeskyDivision of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.
University of Bern · CHUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous vertebroplasty (VP) and balloon kyphoplasty (BKP) for treating painful osteoporotic vertebral fractures are controversial.

objectiveWe assessed the regional variation in the use of VP/BKP in Switzerland.

methodsWe conducted a population-based small area variation analysis using patient discharge data for VP/BKP from all Swiss hospitals and Swiss census data for calendar years 2012/13. We derived hospital service areas (HSAs) by analyzing patient flows, assigning regions from which most residents were discharged to the same VP/BKP specific HSA. We calculated age-/sex-standardized mean VP/BKP-rates and measures of regional variation (extremal quotient [EQ], systematic component of variation [SCV]). We estimated the reduction in variation of VP/BKP rates using negative binomial regression, with adjustment for patient demographic and regional socioeconomic factors (socioeconomic status, urbanization, and language region). We considered the residual, unexplained variation most likely to be unwarranted.

resultsOverall, 4955 VP/BKPs were performed in Switzerland in 2012/13. The age-/sex-standardized mean VP/BKP rate was 4.6/10,000 persons and ranged from 1.0 to 10.1 across 26 HSAs. The EQ was 10.2 and the SCV 57.6, indicating a large variation across VP/BKP specific HSAs. After adjustment for demographic and socioeconomic factors, the total reduction in variance was 32.2% only, with the larger part of the variation remaining unexplained.

conclusionsWe found a 10-fold variation in VP/BKP rates across Swiss VP/BKP specific HSAs. As only one third of the variation was explained by differences in patient demographics and regional socioeconomic factors, VP/BKP in the highest-use areas may, at least partially, represent overtreatment.

Indexed as

KyphoplastyVertebroplastyAgedAged, 80 and overCatchment Area, HealthDemographyFemaleHumansMaleMiddle AgedOsteoporotic FracturesSmall-Area AnalysisSocioeconomic FactorsSpinal FracturesSwitzerland

Identifiers

PMID30532141
PMCPMC6287855
OpenAlexW2905544047

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.