Evidence map›Paper›PMID 30532059›Full record

ReviewNature structural & molecular biology2019

Nucleosome structure and dynamics are coming of age.

Keda Zhou, Guillaume Gaullier, Karolin Luger

Open access · greenAbstract readReview
In one paragraph

Review in Nature structural & molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 200 papers.

0numbers the graph read from it
0cells of the map it votes in
200citing papers in PubMed
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

200 citing papers in PubMed, 349 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Epigenetic regulation and ROS signaling in plant stress adaptation: an integrated framework.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. A Chromatin Biology Assessment of AlphaFold3.bioRxiv : the preprint server for biology · 2026
    Article
  9. Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome.Acta crystallographica. Section D, Structural biology · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. EnDeep4mC predicts DNAGenome research · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

140 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Keda ZhouDepartment of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.
Guillaume GaullierDepartment of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.ORCID http://orcid.org/0000-0003-3405-6021
Karolin LugerDepartment of Biochemistry, University of Colorado Boulder, Boulder, CO, USA. karolin.luger@colorado.edu.ORCID http://orcid.org/0000-0001-5136-5331
Howard Hughes Medical Institute · USUniversity of Colorado Boulder · US

Funding

Structure and Mechanism of Chromatin-Bound PARP1R01CA218255 · NCI · UNIVERSITY OF COLORADO · PI Karolin Luger · 2017 to 2026
$4.5M
NCI NIH HHS R01 CA218255
6 · The paper itself

Abstract

Since the first high-resolution structure of the nucleosome was reported in 1997, the available information on chromatin structure has increased very rapidly. Here, we review insights derived from cutting-edge biophysical and structural approaches applied to the study of nucleosome dynamics and nucleosome-binding factors, with a focus on the experimental advances driving the research. In addition, we highlight emerging challenges in nucleosome structural biology.

Indexed as

ChromatinHistonesHumansModels, TheoreticalNucleosomesChromatinHistonesNucleosomes

Identifiers

PMID30532059
PMCPMC7386248
OpenAlexW2903457010

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.