Evidence map›Paper›PMID 30531968›Full record

ReviewPediatric research2019

Nurturing the preterm infant brain: leveraging neuroplasticity to improve neurobehavioral outcomes.

Dana DeMaster, Johanna Bick, Ursula Johnson, Janelle J Montroy, Susan Landry, Andrea F Duncan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dana DeMasterDepartment of Pediatrics, Children's Learning Institute, University of Texas Health Science Center at Houston, Houston, TX, USA. Dana.M.Demaster@uth.tmc.edu.
Johanna BickDepartment of Psychology, University of Houston, Houston, TX, USA.
Ursula JohnsonDepartment of Pediatrics, Children's Learning Institute, University of Texas Health Science Center at Houston, Houston, TX, USA.
Janelle J MontroyDepartment of Pediatrics, Children's Learning Institute, University of Texas Health Science Center at Houston, Houston, TX, USA.
Susan LandryDepartment of Pediatrics, Children's Learning Institute, University of Texas Health Science Center at Houston, Houston, TX, USA.
Andrea F DuncanDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An intrinsic feature of the developing brain is high susceptibility to environmental influence-known as plasticity. Research indicates cascading disruption to neurological development following preterm (PT) birth; yet, the interactive effects of PT birth and plasticity remain unclear. It is possible that, with regard to neuropsychological outcomes in the PT population, plasticity is a double-edged sword. On one side, high plasticity of rapidly developing neural tissue makes the PT brain more vulnerable to injury resulting from events, including inflammation, hypoxia, and ischemia. On the other side, plasticity may be a mechanism through which positive experience can normalize neurological development for PT children. Much of the available literature on PT neurological development is clinically weighted and focused on diagnostic utility for predicting long-term outcomes. Although diagnostic utility is valuable, research establishing neuroprotective factors is equally beneficial. This review will: (1) detail specific mechanisms through which plasticity is adaptive or maladaptive depending on the experience; (2) integrate research from neuroimaging, intervention, and clinical science fields in a summary of findings suggesting inherent plasticity of the PT brain as a mechanism to improve child outcomes; and (3) summarize how responsive caregiving experiences situate parents as agents of change in normalizing PT infant brain development.

Indexed as

Infant, PrematureNeuronal PlasticityAnimalsBrainCentral Nervous System DiseasesChild, PreschoolHumansInfantInfant, Newborn

Identifiers

PMID30531968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.