Evidence map›Paper›PMID 30531962›Full record

ArticleScientific reports2018

T cell-derived lymphotoxin limits Th1 response during HSV-1 infection.

Kaiting Yang, Yong Liang, Zhichen Sun, Longchao Liu, Jing Liao, Hairong Xu, Mingzhao Zhu, Yang-Xin Fu, Hua Peng

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kaiting YangKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Yong LiangKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Zhichen SunKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Longchao LiuDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Jing LiaoKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Hairong XuKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Mingzhao ZhuKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.ORCID http://orcid.org/0000-0003-2001-2669
Yang-Xin FuDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. yang-xin.fu@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-4809-825X
Hua PengKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. hpeng@moon.ibp.ac.cn.
Chinese Academy of Sciences · CNSouthwestern Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

China Postdoctoral Science Foundation 2016M600139National Natural Science Foundation of China (National Science Foundation of China) 81220108018National Natural Science Foundation of China (National Science Foundation of China) 81471579
6 · The paper itself

Abstract

Though lymphotoxin (LT) is highly expressed by type I helper T (Th1) cells, its contribution to CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesHerpes SimplexHerpesvirus 1, HumanInterleukin-12Lymphotoxin-alphaLymphotoxin beta ReceptorMiceMice, Inbred C57BLMice, TransgenicMonocytesSignal TransductionTh1 CellsUp-RegulationInterleukin-12Lymphotoxin-alphaLymphotoxin beta Receptor

Identifiers

PMID30531962
PMCPMC6286317
OpenAlexW2903246683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.