Evidence map›Paper›PMID 30531950›Full record

ArticleScientific data2018

Nationwide registry of sepsis patients in Japan focused on disseminated intravascular coagulation 2011-2013.

Mineji Hayakawa, Kazuma Yamakawa, Shinjiro Saito, Shigehiko Uchino, Daisuke Kudo, Yusuke Iizuka, Masamitsu Sanui, Kohei Takimoto, Toshihiko Mayumi

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

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  17. Age Is Associated With the Efficacy of Anticoagulant Therapies Against Sepsis-Induced Disseminated Intravascular Coagulation.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
  18. Supernormal Antithrombin Activity Is an Independent Predictor of In-Hospital Mortality in Patients With Sepsis: A Retrospective Observational Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Mineji HayakawaEmergency and Critical Care Center, Hokkaido University Hospital, Sapporo, 060-8648 Japan.
Kazuma YamakawaDivision of Trauma and Surgical Critical Care, Osaka General Medical Center, Osaka, 565-0871 Japan.
Shinjiro SaitoIntensive Care Unit, Department of Anesthesiology, Jikei University School of Medicine, Tokyo, 105-8471 Japan.
Shigehiko UchinoIntensive Care Unit, Department of Anesthesiology, Jikei University School of Medicine, Tokyo, 105-8471 Japan.
Daisuke KudoDivision of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574 Japan.
Yusuke IizukaDepartment of Anesthesiology and Critical Care Medicine, Jichi Medical University Saitama Medical Center, Saitama, 330-8503 Japan.
Masamitsu SanuiDepartment of Anesthesiology and Critical Care Medicine, Jichi Medical University Saitama Medical Center, Saitama, 330-8503 Japan.
Kohei TakimotoDepartment of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Osaka, 565-0871 Japan.
Toshihiko MayumiDepartment of Emergency Medicine, University of Occupational and Environmental Health, Kitakyuusyu, 807-8556 Japan.
Jikei University School of Medicine · JPHokkaido University Hospital · JPJichi Medical University · JPOsaka City General Hospital · JPOsaka University · JPShonan Kamakura General Hospital · JPTohoku University · JPUniversity of Occupational and Environmental Health Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a syndrome with physiologic, pathologic, and biochemical abnormalities induced by infection. Sepsis can induce the dysregulation of systemic coagulation and fibrinolytic systems, resulting in disseminated intravascular coagulation (DIC), which is associated with a high mortality rate. Although there is no international consensus on available treatments for sepsis-induced DIC, DIC diagnosis and treatment are commonly performed in Japanese clinical settings. Therefore, clinical data related to sepsis-induced DIC diagnosis and treatment can be obtained from Japanese clinical settings. We performed a retrospective nationwide observational study (Japan Septic Disseminated Intravascular Coagulation [J-SEPTIC DIC] study) to collect data regarding characteristics of sepsis patients in Japan, with a focus on coagulofibrinolytic dysregulation and DIC treatment received by each patient. The J-SEPTIC DIC study collected information for a total of 3,195 patients with severe sepsis and septic shock and is the largest data set in Japan on DIC diagnosis and treatment in clinical settings.

Indexed as

Disseminated Intravascular CoagulationRegistriesSepsisHumansJapanRetrospective Studies

Identifiers

PMID30531950
PMCPMC6289115
OpenAlexW2903829945

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.