Evidence map›Paper›PMID 30531858›Full record

ArticleTranslational psychiatry2018

Ventral striatal dopamine transporter availability is associated with lower trait motor impulsivity in healthy adults.

Christopher T Smith, M Danica San Juan, Linh C Dang, Daniel T Katz, Scott F Perkins, Leah L Burgess, Ronald L Cowan, H Charles Manning, Michael L Nickels, Daniel O Claassen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Accentuated Paralimbic and Reduced Mesolimbic DThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  5. Repeated Cocaine Intake Differentially Impacts Striatal DInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. The effects of early life stress on impulsivity.Neuroscience and biobehavioral reviews · 2022
    Review
  10. Frontiers in psychiatry · 2022
    Article
  11. Review
  12. Article
  13. Which came first: Cannabis use or deficits in impulse control?Progress in neuro-psychopharmacology & biological psychiatry · 2021
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Christopher T SmithDepartment of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN, 37240-7817, USA. christopher.t.smith@vanderbilt.edu.ORCID http://orcid.org/0000-0002-8212-7886
M Danica San JuanDepartment of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN, 37240-7817, USA.
Linh C DangDepartment of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN, 37240-7817, USA.
Daniel T KatzDepartment of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN, 37240-7817, USA.
Scott F PerkinsDepartment of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN, 37240-7817, USA.
Leah L BurgessDepartment of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN, 37240-7817, USA.
Ronald L CowanDepartment of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN, 37240-7817, USA.
H Charles ManningDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Medical Center North, 1161 21st Avenue South, Nashville, TN, 37232, USA.
Michael L NickelsDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Medical Center North, 1161 21st Avenue South, Nashville, TN, 37232, USA.
Daniel O ClaassenDepartment of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, A-0118, Nashville, TN, 37232-2551, USA.
Gregory R Samanez-LarkinDepartment of Psychology and Neuroscience, Duke University, 417 Chapel Drive, Durham, NC, 27708, USA.
David H ZaldDepartment of Psychology, PMB 407817, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN, 37240-7817, USA.
Vanderbilt University · USVanderbilt University Medical Center · USDuke University · US

Funding

Dopaminergic Neuromodulation of Decision Making in Young and Middle-Aged AdultsR01AG043458 · NIA · VANDERBILT UNIVERSITY · PI SAMANEZ LARKIN, GREGORY R, ZALD, DAVID HAROLD · 2014 to 2018
$2.3M
Biological Determinants of Impulsivity in Parkinson's DiseaseR01NS097783 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CLAASSEN, DANIEL OLIVER · 2016 to 2020
$2.2M
Neuromodulation of Motivated Cognition and Decision Making Across AdulthoodR00AG042596 · NIA · YALE UNIVERSITY · PI SAMANEZ LARKIN, GREGORY R · 2014 to 2016
$730k
Radiofluorination Equipment for PET Imaging ResearchS10OD019963 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MANNING, HENRY CHARLES · 2016 to 2016
$291k
Linking Temporal Differences in d-Amphetamine Subjective Effects to DRD2 and DATF32DA041157 · NIDA · VANDERBILT UNIVERSITY · PI SMITH, CHRISTOPHER THOMAS · 2016 to 2018
$174k
Dopamine function in reward-driven decision makingF32DA036979 · NIDA · VANDERBILT UNIVERSITY · PI DANG, LINH CAT · 2015 to 2017
$173k
NIA NIH HHS R00 AG042596NIA NIH HHS R01 AG043458NIDA NIH HHS F32 DA036979NIDA NIH HHS F32 DA041157NIH HHS S10 OD019963NINDS NIH HHS R01 NS097783
6 · The paper itself

Abstract

Impulsivity is a transdiagnostic feature of a range of externalizing psychiatric disorders. Preclinical work links reduced ventral striatal dopamine transporter (DAT) availability with heightened impulsivity and novelty seeking. However, there is a lack of human data investigating the relationship between DAT availability, particularly in subregions of the striatum, and the personality traits of impulsivity and novelty seeking. Here we collected PET measures of DAT availability (BP

Indexed as

PersonalityAdultAgedDopamine Plasma Membrane Transport ProteinsExploratory BehaviorFemaleFluorodeoxyglucose F18HumansImpulsive BehaviorMaleMiddle AgedPersonality InventoryPositron-Emission TomographyVentral StriatumYoung AdultDopamine Plasma Membrane Transport ProteinsFluorodeoxyglucose F18SLC6A3 protein, human

Identifiers

PMID30531858
PMCPMC6286354
OpenAlexW2903597339

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.