Evidence map›Paper›PMID 30531821›Full record

Trial reportNutrition & diabetes2018

Effect of dried fruit on postprandial glycemia: a randomized acute-feeding trial.

Effie Viguiliouk, Alexandra L Jenkins, Sonia Blanco Mejia, John L Sievenpiper, Cyril W C Kendall

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrition & diabetes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02960373 (Dried Fruit as a Means for Lowering the Glycemic Response to High Glycemic Index-carbohydrate Foods), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02960373 naunknown statusnot on this map

Dried Fruit as a Means for Lowering the Glycemic Response to High Glycemic Index-carbohydrate Foods

TypeinterventionalSponsorUniversity of TorontoRan2016Enrolled10ConditionsPreDiabetes, Diabetes Mellitus, DysglycemiaArmsWhite Bread (Control), Dried Fruit - Glycemic Index, Catalytic Fructose Dose Effect, High GI Displacement Effect
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Effie ViguilioukToronto 3D Knowledge Synthesis and Clinical Trials Unit, St. Michael's Hospital, Toronto, Canada.
Alexandra L JenkinsToronto 3D Knowledge Synthesis and Clinical Trials Unit, St. Michael's Hospital, Toronto, Canada.
Sonia Blanco MejiaToronto 3D Knowledge Synthesis and Clinical Trials Unit, St. Michael's Hospital, Toronto, Canada.
John L SievenpiperToronto 3D Knowledge Synthesis and Clinical Trials Unit, St. Michael's Hospital, Toronto, Canada. john.sievenpiper@utoronto.ca.
Cyril W C KendallToronto 3D Knowledge Synthesis and Clinical Trials Unit, St. Michael's Hospital, Toronto, Canada. cyril.kendall@utoronto.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTo investigate the effect of dried fruit in modifying postprandial glycemia, we assessed the ability of 4 dried fruits (dates, apricots, raisins, sultanas) to decrease postprandial glycemia through three mechanisms: a glycemic index (GI) effect, displacement effect, or 'catalytic' fructose effect. SUBJECTS/

methodsWe conducted an acute randomized, multiple-crossover trial in an outpatient setting in 10 healthy adults. Participants received 3 white bread control meals and 12 dried fruit test meals in random order. The test meals included each of 4 dried fruits (dates, apricots, raisins, sultanas) alone (GI effect), 4 of the dried fruits displacing half the available carbohydrate in white bread (displacement effect), or 4 of the dried fruits providing a small 'catalytic' dose (7.5 g) of fructose added to white bread ('catalytic' fructose effect). The protocol followed the ISO method for the determination of GI (ISO 26642:2010). The primary outcome was mean ± SEM GI (glucose scale) for ease of comparison across the three mechanisms.

resultsTen healthy participants (7 men, 3 women; mean ± SD age and BMI: 39 ± 12 years and 25 ± 2 kg/m

conclusionsIn conclusion, dried fruits have a lower GI and reduce the glycemic response of white bread through displacement of half of the available carbohydrate. Longer-term randomized trials are needed to confirm whether dried fruit can contribute to sustainable improvements in glycemic control.

trial registrationClinicalTrials.gov identifier, NCT02960373.

Indexed as

FruitAdultBlood GlucoseCross-Over StudiesFemaleHumansMaleMiddle AgedPostprandial PeriodBlood Glucose

Identifiers

PMID30531821
PMCPMC6288147

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.