Evidence map›Paper›PMID 30531817›Full record

ArticleNature communications2018

A machine learning approach for online automated optimization of super-resolution optical microscopy.

Audrey Durand, Theresa Wiesner, Marc-André Gardner, Louis-Émile Robitaille, Anthony Bilodeau, Christian Gagné, Paul De Koninck, Flavie Lavoie-Cardinal

Abstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  7. Live-cell imaging powered by computation.Nature reviews. Molecular cell biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Audrey DurandDépartement de génie électrique et de génie informatique, Université Laval, Québec, QC, G1V 0A6, Canada. audrey.durand@mcgill.ca.
Theresa WiesnerCERVO Brain Research Center, 2601 de la Canardière, Québec, QC, G1J 2G3, Canada.
Marc-André GardnerDépartement de génie électrique et de génie informatique, Université Laval, Québec, QC, G1V 0A6, Canada.
Louis-Émile RobitailleDépartement de génie électrique et de génie informatique, Université Laval, Québec, QC, G1V 0A6, Canada.
Anthony BilodeauCERVO Brain Research Center, 2601 de la Canardière, Québec, QC, G1J 2G3, Canada.
Christian GagnéDépartement de génie électrique et de génie informatique, Université Laval, Québec, QC, G1V 0A6, Canada.
Paul De KoninckCERVO Brain Research Center, 2601 de la Canardière, Québec, QC, G1J 2G3, Canada.
Flavie Lavoie-CardinalCERVO Brain Research Center, 2601 de la Canardière, Québec, QC, G1J 2G3, Canada. flavie.lavoie-cardinal.1@ulaval.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional approaches for finding well-performing parameterizations of complex imaging systems, such as super-resolution microscopes rely on an extensive exploration phase over the illumination and acquisition settings, prior to the imaging task. This strategy suffers from several issues: it requires a large amount of parameter configurations to be evaluated, it leads to discrepancies between well-performing parameters in the exploration phase and imaging task, and it results in a waste of time and resources given that optimization and final imaging tasks are conducted separately. Here we show that a fully automated, machine learning-based system can conduct imaging parameter optimization toward a trade-off between several objectives, simultaneously to the imaging task. Its potential is highlighted on various imaging tasks, such as live-cell and multicolor imaging and multimodal optimization. This online optimization routine can be integrated to various imaging systems to increase accessibility, optimize performance and improve overall imaging quality.

Identifiers

PMID30531817
PMCPMC6286316

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.