Evidence map›Paper›PMID 30531561›Full record

ArticleObstetrics and gynecology2019

The Language of First-Trimester Nonviable Pregnancy: Patient-Reported Preferences and Clarity.

Elizabeth G Clement, Sarah Horvath, Arden McAllister, Nathanael C Koelper, Mary D Sammel, Courtney A Schreiber

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Obstetrics and gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02012491 (Comparative Effectiveness of Pregnancy Failure Management Regimens), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02012491 phase3completednot on this map

Comparative Effectiveness of Pregnancy Failure Management Regimens

TypeinterventionalSponsorUniversity of PennsylvaniaRan2014 to 2019Enrolled300ConditionsSpontaneous AbortionArmsMisoprostol, Mifepristone
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Elizabeth G ClementDepartment of Obstetrics and Gynecology, Division of General Obstetrics and Gynecology, the Division of Family Planning, and the Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Sarah Horvath
Arden McAllister
Nathanael C Koelper
Mary D Sammel
Courtney A Schreiber
Twitter (United States) · US

Funding

Comparative Effectiveness of Pregnancy Failure Management Regimens (Pre-Fai-R)R01HD071920 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI SCHREIBER, COURTNEY A. · 2013 to 2017
$2.8M
NICHD NIH HHS R01 HD071920
6 · The paper itself

Abstract

objectiveTo document the terminology patients hear during the treatment course for a nonviable pregnancy and to ask patients their perceived clarity and preference of terminology to identify a patient-centered lexicon.

methodsWe performed a preplanned substudy survey of English-speaking participants in New York, Pennsylvania, and California at the time of enrollment in a randomized multisite trial of medical management of first-trimester early pregnancy loss. The six-item survey, administered on paper or an electronic tablet, was developed and piloted for internal and external validity. We used a visual analog scale and quantified tests of associations between participant characteristics and survey responses using risk ratios.

resultsWe approached 155 English-speaking participants in the parent study, of whom 145 (93.5%) participated. In the process of receiving their diagnosis from a clinician, participants reported hearing the terms "miscarriage" (n=109 [75.2%]) and "early pregnancy loss" (n=73 [50.3%]) more than "early pregnancy failure" (n=31 [21.3%]) and "spontaneous abortion" (n=21 [14.4%]). The majority selected "miscarriage" (n=79 [54.5%]) followed by "early pregnancy loss" (n=49 [33.8%]) as their preferred term. In multivariable models controlling for study site, ethnicity, race, history of induced abortion, and whether the current pregnancy was planned, women indicated that "spontaneous abortion" and "early pregnancy failure" were significantly less clear than "early pregnancy loss" (53/145, adjusted risk ratio 0.12, 95% CI 0.07-0.19 and 92/145, adjusted risk ratio 0.38, 95% CI 0.24-0.61, respectively, as compared with 118/145 for "early pregnancy loss"). "Miscarriage" scored similarly to "early pregnancy loss" in clarity (119/145, adjusted risk ratio 1.05, 95% CI 0.62-1.77).

conclusionThe terminology used to communicate "nonviable pregnancy in the first trimester" is highly variable. In this cohort of women, most preferred the term "miscarriage" and classified both "miscarriage" and "early pregnancy loss" as clear labels for a nonviable pregnancy. Health care providers can use these terms to enhance patient-clinician communication. CLINICAL

trial registrationClinicalTrials.gov, NCT02012491.

Indexed as

Abortion, SpontaneousCommunication BarriersPatient PreferenceAdultCaliforniaFemaleHumansPennsylvaniaPregnancyPregnancy Trimester, FirstSurveys and QuestionnairesTerminology as Topic

Identifiers

PMID30531561
PMCPMC10302403
OpenAlexW2905296718

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.