Evidence map›Paper›PMID 30531535›Full record

ReviewCurrent opinion in critical care2019

Optimizing respiratory management in resource-limited settings.

Rebecca Inglis, Emmanuel Ayebale, Marcus J Schultz

Registry-linked trialAbstract readReview
In one paragraph

Review in Current opinion in critical care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06288724 (Potentially MOdifiable Factors To ImproVe Outcomes of Mechanically Ventilated Patients in ICUs in a Low-income Country), which is not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06288724 unknown statusnot on this mapstarted 2024, after this paper: background citation

Potentially MOdifiable Factors To ImproVe Outcomes of Mechanically Ventilated Patients in ICUs in a Low-income Country: Rationale and Protocol for a Registry-embedded Prospective Observational Study

Typeobservational_patient_registrySponsorNat Intensive Care Surveillance - MORURan2024 to 2024Enrolled625ConditionsCritical Illness, Invasive Mechanical Ventilation, ICU Mortality, Developing Countries
3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Respiratory Emergencies in Disasters: A Narrative Review.Thoracic research and practice · 2026
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  13. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rebecca InglisLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Mahosot Hospital, Vientiane, Lao People's Democratic Republic.
Emmanuel AyebaleDepartment of Anaesthesia, Makerere University, Kampala, Uganda.
Marcus J SchultzDepartment of Intensive Care.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review focuses on the emerging body of literature regarding the management of acute respiratory failure in low- and middle-income countries (LMICs). The aim is to abstract management principles that are of relevance across a variety of settings where resources are severely limited. RECENT

findingsMechanical ventilation is an expensive intervention associated with considerable mortality and a high rate of iatrogenic complications in many LMICs. Recent case series report crude mortality rates for ventilated patients of between 36 and 72%. Measures to avert the need for invasive mechanical ventilation in LMICs are showing promise: bubble continuous positive airway pressure has been demonstrated to decrease mortality in children with acute respiratory failure and trials suggest that noninvasive ventilation can be conducted safely in settings where resources are low. SUMMARY: The management of patients with acute respiratory failure in LMICs should focus on avoiding intubation where possible, improving the safety of mechanical ventilation and expediting weaning. Future directions should involve the development and trialing of robust and context-appropriate respiratory support technology.

Indexed as

Noninvasive VentilationRespiratory Distress SyndromeRespiratory InsufficiencyChildContinuous Positive Airway PressureHumansRespiration, Artificial

Identifiers

PMID30531535
PMCPMC6319564

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.