Evidence map›Paper›PMID 30531319›Full record

ArticleAIDS (London, England)2019

Systemic inflammation is elevated among both HIV-uninfected and HIV-infected young MSM.

Ethan Morgan, Harry E Taylor, Daniel Timothy Ryan, Richard D'Aquila, Brian Mustanski

Abstract read
In one paragraph

Article in AIDS (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 25 citations in OpenAlex.

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  6. HIV, inflammation, and initiation of methamphetamine use in sexual and gender minorities assigned male at birth.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ethan MorganNorthwestern University, Chicago, IL, USA.
Harry E Taylor
Daniel Timothy Ryan
Richard D'Aquila
Brian Mustanski
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Kathryn Rose Macapagal · 2015 to 2026
$38.4M
The RADAR cohort study of multilevel Influences on HIV and substance useU01DA036939 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian Mustanski, Michael E Newcomb · 2014 to 2026
$29.5M
Substance Use, Stress, and HIV Influences on Systemic Inflammation Among Young Men Who Have Sex With MenF32DA046313 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MORGAN, ETHAN · 2018 to 2019
$119k
NCATS NIH HHS UL1 TR001422NIAID NIH HHS P30 AI117943NIDA NIH HHS F32 DA046313NIDA NIH HHS U01 DA036939
6 · The paper itself

Abstract

: Evidence suggests that systemic inflammation increases due to HIV infection. C-reactive protein (CRP), interleukin (IL)-6 and tumour necrosis factor (TNF)-α values were compared between HIV-positive and HIV-negative young MSM and transgender women. CRP values were more than 3 mg/l among 49.8% of participants. HIV status was not significantly associated with CRP nor IL-6. TNF-α was significantly higher among HIV-positive participants. These results suggest the need for further study of the causes and health consequences of elevated systemic inflammation among this population.

Indexed as

Homosexuality, MaleAdolescentAdultC-Reactive ProteinHIV InfectionsHumansInflammationInterleukin-6Longitudinal StudiesMaleTumor Necrosis Factor-alphaYoung AdultC-Reactive ProteinIL6 protein, humanInterleukin-6TNF protein, humanTumor Necrosis Factor-alpha

Identifiers

PMID30531319
PMCPMC6399025
OpenAlexW2903527436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.