ReviewNeural regeneration research2019
Aging gracefully: social engagement joins exercise and enrichment as a key lifestyle factor in resistance to age-related cognitive decline.
Review in Neural regeneration research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed.
- Augmenting Computerized Cognitive Training With Vortioxetine for Age-Related Cognitive Decline: A Randomized Controlled Trial.The American journal of psychiatry · 2020Trial
- Living arrangements and cognitive resilience in aging: unraveling distinct pathways through plasma biomarkers.The journal of prevention of Alzheimer's disease · 2026Article
- Aging effects on emotionality, cognition and brain mononuclear cells in Sprague-Dawley rats of both sexes.npj aging · 2026Article
- Development and validation of a nomogram for predicting the risk of cognitive impairment among chronic obstructive pulmonary diseases.Annals of medicine · 2025Article
- Aging as a Loss of Goal-Directedness: An Evolutionary Simulation and Analysis Unifying Regeneration with Anatomical Rejuvenation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- 24-hour activity cycle behaviors and gray matter volume in mild cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- From Steps to Context: Optimizing Digital Phenotyping for Physical Activity Monitoring in Older Adults by Integrating Wearable Data and Ecological Momentary Assessment.Sensors (Basel, Switzerland) · 2025Article
- Prevalence and associated factors of healthy aging among community-dwelling older adults in Lishui city, China: a cross-sectional study.BMC public health · 2025Article
- HIV Stigma is Associated with Two-Year Decline in Cognitive Performance Among People with HIV.AIDS and behavior · 2025Article
- Article
- Constructing a dual-path motivation-regulation model of elderly sport consumption: a psychological perspective on behavioral drivers.Frontiers in psychology · 2025Review
- The BDNF-Interactive Model for Sustainable Hippocampal Neurogenesis in Humans: Synergistic Effects of Environmentally-Mediated Physical Activity, Cognitive Stimulation, and Mindfulness.International journal of molecular sciences · 2024Review
- APOE ε4 carrier status moderates the effect of lifestyle factors on cognitive reserve.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- The Mediating Role of Cortical Atrophy on the Relationship between the Resilience Index and Cognitive Function: Findings from the Healthy Brain Initiative.Journal of Alzheimer's disease : JAD · 2024Article
- Age-related social selectivity: An adaptive lens on a later life social phenotype.Neuroscience and biobehavioral reviews · 2023Review
- Musical and Multilingual Experience Are Related to Healthy Aging: Better Some Than None But Even Better Together.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- [Cognitive and psychoemotional changes in menopausal transition: The possibility of medical correction].Problemy endokrinologii · 2023Article
- Age-specific findings on lifestyle and trajectories of cognitive function from the Korean Longitudinal Study of Aging.Epidemiology and health · 2023Article
- Nutritional status, alcohol-tobacco consumption behaviour and cognitive decline among older adults in India.Scientific reports · 2022Article
- Contributions of early-life cognitive reserve and late-life leisure activity to successful and pathological cognitive aging.BMC geriatrics · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Cognitive impairment is a consequence of the normal aging process that effects many species, including humans and rodent models. Decline in hippocampal memory function is especially prominent with age and often reduces quality of life. As the aging population expands, the need for interventional strategies to prevent cognitive decline has become more pressing. Fortunately, several major lifestyle factors have proven effective at combating hippocampal aging, the most well-known of which are environmental enrichment and exercise. While the evidence supporting the beneficial nature of these factors is substantial, a less well-understood factor may also contribute to healthy cognitive aging: social engagement. We review the evidence supporting the role of social engagement in preserving hippocampal function in old age. In elderly humans, high levels of social engagement correlate with better hippocampal function, yet there is a dearth of work to indicate a causative role. Existing rodent literature is also limited but has begun to provide causative evidence and establish candidate mechanisms. Summed together, while many unanswered questions remain, it is clear that social engagement is a viable lifestyle factor for preserving cognitive function in old age. Social integration across the lifespan warrants more investigation and more appreciation when designing living circumstances for the elderly.
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