Evidence map›Paper›PMID 30531010›Full record

ArticleNeural regeneration research2019

Diffusion kurtosis imaging of microstructural changes in brain tissue affected by acute ischemic stroke in different locations.

Liu-Hong Zhu, Zhong-Ping Zhang, Fu-Nan Wang, Qi-Hua Cheng, Gang Guo

Abstract read
In one paragraph

Article in Neural regeneration research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liu-Hong ZhuDepartment of Radiology, Xiamen Second Hospital; Department of Radiology, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen, Fujian Province, China.
Zhong-Ping ZhangMR Research China, GE Healthcare, Beijing, China.
Fu-Nan WangDepartment of Radiology, Xiamen Second Hospital, Xiamen, Fujian Province, China.
Qi-Hua ChengDepartment of Radiology, Xiamen Second Hospital, Xiamen, Fujian Province, China.
Gang GuoDepartment of Radiology, Xiamen Second Hospital, Xiamen, Fujian Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The location of an acute ischemic stroke is associated with its prognosis. The widely used Gaussian model-based parameter, apparent diffusion coefficient (ADC), cannot reveal microstructural changes in different locations or the degree of infarction. This prospective observational study was reviewed and approved by the Institutional Review Board of Xiamen Second Hospital, China (approval No. 2014002).Diffusion kurtosis imaging (DKI) was used to detect 199 lesions in 156 patients with acute ischemic stroke (61 males and 95 females), mean age 63.15 ± 12.34 years. A total of 199 lesions were located in the periventricular white matter (n = 52), corpus callosum (n = 14), cerebellum (n = 29), basal ganglia and thalamus (n = 21), brainstem (n = 21) and gray-white matter junctions (n = 62). Percentage changes of apparent diffusion coefficient (ΔADC) and DKI-derived indices (fractional anisotropy [ΔFA], mean diffusivity [ΔMD], axial diffusivity [ΔD

Indexed as

1.5 Tesla magnetic resonance systemacute ischemic strokeapparent diffusion coefficientdiffusion kurtosis imagingdiffusion weighted imagingmean kurtosismicrostructure changesnerve regenerationneural regenerationwhite matter

Identifiers

PMID30531010
PMCPMC6301161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.