Evidence map›Paper›PMID 30530859›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Changes in Endogenous Dopamine Induced by Methylphenidate Predict Functional Connectivity in Nonhuman Primates.

Rasmus M Birn, Alexander K Converse, Abigail Z Rajala, Andrew L Alexander, Walter F Block, Alan B McMillan, Bradley T Christian, Caitlynn N Filla, Dhanabalan Murali, Samuel A Hurley and 2 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Acetylcholine and noradrenaline enhance foraging optimality in humans.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Trial
  5. Trial
  6. Trial
  7. A next generation neural mass model with neuromodulation.Journal of computational neuroscience · 2026
    Article
  8. Review
  9. Examining the role of dopamine in methylphenidate's effects on resting brain function.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Methylphenidate modulates motor cortical dynamics and behavior.bioRxiv : the preprint server for biology · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Advances in simultaneous PET/MR for imaging neuroreceptor function.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Rasmus M BirnDepartment of Psychiatry, University of Wisconsin-Madison, Madison, Wisconsin 53719.
Alexander K ConverseWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705.ORCID 0000-0002-2035-9331
Abigail Z RajalaDepartment of Neuroscience, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Andrew L AlexanderDepartment of Psychiatry, University of Wisconsin-Madison, Madison, Wisconsin 53719.
Walter F BlockDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Madison, Wisconsin 53705.
Alan B McMillanDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, 53792, and.
Bradley T ChristianWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Caitlynn N FillaDepartment of Neuroscience, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Dhanabalan MuraliDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Madison, Wisconsin 53705.
Samuel A HurleyDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, 53792, and.
Rick L JenisonDepartment of Neuroscience, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Luis C PopulinDepartment of Neuroscience, University of Wisconsin-Madison, Madison, Wisconsin 53705, lpopulin@wisc.edu.
University of Wisconsin–Madison · USUniversity of Wisconsin System · US

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI POLLAK, SETH D · 2016 to 2020
$6.0M
EXTRAMURAL RES FACIL CONST: REPRODUCTIVE, GROWTH &DVMT, MENOPAUSEC06RR020141 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI CADWALLADER, MARTIN · 2004 to 2004
$3.6M
EXTRAMURAL REGIONAL FACILITIES CONSTRUCTIONC06RR015459 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI CADWALLADER, MARTIN · 2000 to 2000
$1.9M
NCRR NIH HHS C06 RR015459NCRR NIH HHS C06 RR020141NICHD NIH HHS U54 HD090256NIH HHS P51 OD011106
6 · The paper itself

Abstract

Dopamine (DA) levels in the striatum are increased by many therapeutic drugs, such as methylphenidate (MPH), which also alters behavioral and cognitive functions thought to be controlled by the PFC dose-dependently. We linked DA changes and functional connectivity (FC) using simultaneous [

Indexed as

ConnectomeAnimalsBenzamidesBrain MappingCaudate NucleusDopamineDopamine Plasma Membrane Transport ProteinsDopamine Uptake InhibitorsDose-Response Relationship, DrugFluorine RadioisotopesMacaca mulattaMagnetic Resonance ImagingMaleMethylphenidatePositron-Emission TomographyPrefrontal CortexBenzamidesDopamineDopamine Plasma Membrane Transport ProteinsDopamine Uptake InhibitorsFluorine RadioisotopesMethylphenidateN-((1-allyl-2-pyrrolidinyl)methyl)-5-(3-fluoropropyl)-2,3-dimethoxybenzamidePyrrolidinesRadiopharmaceuticalsdopaminefallypridemethylphenidatePET/MR

Identifiers

PMID30530859
PMCPMC6381257
OpenAlexW2904598629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.