ArticleThe Journal of biological chemistry2018
Genetic code and metabolism: The perpetual waltz.
Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Proline mediates metabolic communication between retinal pigment epithelial cells and the retina.The Journal of biological chemistry · 2019Article
- Celebrating science's next generation.The Journal of biological chemistry · 2019Article
Corrections and comments
- Comment on
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the origin of life, metabolism and protein synthesis have evolved together to balance the vast amounts of ATP and amino acids required for genetic translation with the rest of the cell's energy needs. A new study offers satisfying insights into a long-standing evolutionary mystery surrounding a fused, bifunctional aminoacyl-tRNA synthetase. To avoid depleting cells from an essential amino acid generated by the Krebs cycle, harvesting for Glu and Pro by the translation machinery was unified in animals, thus preventing a Pro-hungry translational apparatus from depleting the cell of essential Glu reserves.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.