Evidence map›Paper›PMID 30530776›Full record

ArticleBlood advances2018

p53 regulates CD46 expression and measles virus infection in myeloma cells.

Anne Lok, Geraldine Descamps, Benoit Tessoulin, David Chiron, Marion Eveillard, Catherine Godon, Yannick Le Bris, Astrid Vabret, Celine Bellanger, Laurent Maillet and 9 more

Abstract read
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  9. Oncolytic viral vectors in the era of diversified cancer therapy: from preclinical to clinical.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  10. Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Anne LokCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Geraldine DescampsCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Benoit TessoulinCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
David ChironCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Marion EveillardCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Catherine GodonLaboratoire d'Hématologie, CHU de Nantes, Nantes, France.
Yannick Le BrisCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Astrid VabretNational Reference Laboratory for Measles Virus, Département de Virologie, CHU de Caen, Université de Normandie, Caen, France; and.
Celine BellangerCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Laurent MailletCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Sophie Barillé-NionCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Marc GregoireCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Jean-François FonteneauCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Steven Le GouillCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Philippe MoreauCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Frederic TangyCNRS UMR3569, Unité de Génomique Virale et Vaccination, Institut Pasteur, Paris, France.
Martine AmiotCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Agnes Moreau-AubryCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.
Catherine Pellat-DeceunynckCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we assessed the sensitivity of myeloma cells to the oncolytic measles virus (MV) in relation to p53 using 37 cell lines and 23 primary samples. We showed that infection and cell death were correlated with CD46 expression, which was associated with

Indexed as

Cell Line, TumorHumansMeasles virusMembrane Cofactor ProteinMicroRNAsMultiple MyelomaProtein BindingReceptors, TNF-Related Apoptosis-Inducing LigandRNA InterferenceRNA, Small InterferingTumor Suppressor Protein p53Membrane Cofactor ProteinMicroRNAsReceptors, TNF-Related Apoptosis-Inducing LigandRNA, Small InterferingTNFRSF10B protein, humanTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID30530776
PMCPMC6290095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.