ArticleProceedings of the National Academy of Sciences of the United States of America2018
Rapid evolution of a skin-lightening allele in southern African KhoeSan.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed.
- Unlocking Ethiopia's genomic landscape and its global significance: a call for inclusive genomics research.Human genomics · 2026Review
- The genetic architecture of human skin pigmentation: evolution and adaptation across global populations.Frontiers in genetics · 2026Review
- Skin phenotype diversity across populations: from skin morphology to molecular phenotype.Frontiers in medicine · 2026Review
- Inference of human pigmentation from ancient DNA by genotype likelihoods.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Sunburn.Eplasty · 2024Article
- Getting it right: Teaching undergraduate biology to undermine racial essentialism.Biology methods & protocols · 2023Article
- The recombination landscape of the Khoe-San likely represents the upper limits of recombination divergence in humans.Genome biology · 2022Article
- Article
- The evolution of human skin pigmentation involved the interactions of genetic, environmental, and cultural variables.Pigment cell & melanoma research · 2021Review
- Evolutionary genetics of skin pigmentation in African populations.Human molecular genetics · 2021Review
- The evolution of skin pigmentation-associated variation in West Eurasia.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Admixed Populations Improve Power for Variant Discovery and Portability in Genome-Wide Association Studies.Frontiers in genetics · 2021Article
- Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations.Communications biology · 2020Article
- The Evolutionary History of Human Skin Pigmentation.Journal of molecular evolution · 2020Review
- Inferring the model and onset of natural selection under varying population size from the site frequency spectrum and haplotype structure.Proceedings. Biological sciences · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Skin pigmentation is under strong directional selection in northern European and Asian populations. The indigenous KhoeSan populations of far southern Africa have lighter skin than other sub-Saharan African populations, potentially reflecting local adaptation to a region of Africa with reduced UV radiation. Here, we demonstrate that a canonical Eurasian skin pigmentation gene,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.