Evidence map›Paper›PMID 30530643›Full record

ArticleG3 (Bethesda, Md.)2019

A Transgenic Flock House Virus Replicon Reveals an RNAi Independent Antiviral Mechanism Acting in

Nelson Martins, Aurélie Lemoine, Estelle Santiago, Simona Paro, Jean-Luc Imler, Carine Meignin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nelson MartinsUniversité de Strasbourg, CNRS, Insect Models of Innate Immunity (M3i, UPR9022), 67084 Strasbourg Cedex c.meignin@unistra.fr nmartins@ibmc-cnrs.unistra.fr.ORCID 0000-0002-3923-2998
Aurélie LemoineUniversité de Strasbourg, CNRS, Insect Models of Innate Immunity (M3i, UPR9022), 67084 Strasbourg Cedex.
Estelle SantiagoUniversité de Strasbourg, CNRS, Insect Models of Innate Immunity (M3i, UPR9022), 67084 Strasbourg Cedex.
Simona ParoUniversité de Strasbourg, CNRS, Insect Models of Innate Immunity (M3i, UPR9022), 67084 Strasbourg Cedex.
Jean-Luc ImlerUniversité de Strasbourg, CNRS, Insect Models of Innate Immunity (M3i, UPR9022), 67084 Strasbourg Cedex c.meignin@unistra.fr nmartins@ibmc-cnrs.unistra.fr.
Carine MeigninUniversité de Strasbourg, CNRS, Insect Models of Innate Immunity (M3i, UPR9022), 67084 Strasbourg Cedex c.meignin@unistra.fr nmartins@ibmc-cnrs.unistra.fr.ORCID 0000-0002-6588-9045
Université de Strasbourg · FRModèles Insectes de l'Immunité Innée · FR

Funding

Sequencing CoreP01AI070167 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI BEUTLER, BRUCE A · 2006 to 2016
$27.2M
NIAID NIH HHS P01 AI070167
6 · The paper itself

Abstract

The small interfering RNA (siRNA) pathway is the main and best studied invertebrate antiviral response. Other poorly characterized protein based antiviral mechanisms also contribute to the control of viral replication in insects. In addition, it remains unclear whether tissue specific factors contribute to RNA and protein-based antiviral immunity mechanisms.

Indexed as

RepliconAnimalsDrosophila melanogasterFemaleHost-Pathogen InteractionsNodaviridaeOvaryRNA, Small InterferingVirus ReplicationRNA, Small InterferingAntiviral ImmunityDrosophila melanogasterFollicular somatic cellsGenetics of ImmunityViral replicon

Identifiers

PMID30530643
PMCPMC6385967
OpenAlexW2903583389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.