Evidence map›Paper›PMID 30530635›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2018

AACR White Paper: Shaping the Future of Cancer Prevention - A Roadmap for Advancing Science and Public Health.

Scott M Lippman, Cory Abate-Shen, Karen L Colbert Maresso, Graham A Colditz, Andrew J Dannenberg, Nancy E Davidson, Mary L Disis, Raymond N DuBois, Eva Szabo, Anna R Giuliano and 11 more

Open access · greenAbstract readConsensus Statement
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
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  5. Adult obesity treatment and prevention: A trans-agency commentary on the research landscape, gaps, and future opportunities.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024
    Review
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  8. Article
  9. Review
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  11. Review
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  13. Review
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  15. Molecular Pathology of Lung Cancer.Cold Spring Harbor perspectives in medicine · 2022
    Review
  16. Article
  17. Article
  18. Frontiers in pharmacology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Scott M LippmanUC San Diego Moores Cancer Center, LaJolla, California. ehawk@mdanderson.org slippman@ucsd.edu.
Cory Abate-ShenDepartments of Urology, Medicine, Systems Biology, and Pathology & Cell Biology, Institute of Cancer Genetics, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY.
Karen L Colbert MaressoDivision of Cancer Prevention & Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX.
Graham A ColditzDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Andrew J DannenbergWeill Cornell Medical College, New York, NY.
Nancy E DavidsonFred Hutchinson Cancer Center and University of Washington, Seattle, Washington.
Mary L DisisUW Medicine Cancer Vaccine Institute, University of Washington, Seattle, Washington.
Raymond N DuBoisDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.
Eva SzaboDivision of Cancer Prevention, National Cancer Institute, NIH, Bethesda, Maryland.
Anna R GiulianoCenter for Infection Research in Cancer, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.
William N HaitJanssen Research and Development LLC., Raritan, New Jersey.
J Jack LeeDepartment of Biostatistics, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Thomas W KenslerPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Barnett S KramerDivision of Cancer Prevention, NCI, Bethesda, Maryland.
Paul LimburgDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Anirban MaitraSheikh Ahmed Pancreatic Cancer Research Center, University of Texas MD Anderson Cancer Center, Houston, TX.
Maria Elena MartinezDepartment of Family Medicine and Public Health, UC San Diego, LaJolla, California.
Timothy R RebbeckCancer Epidemiology & Cancer Risk and Disparity, Dana-Farber Cancer Institute, Boston, MA.
Kathryn H SchmitzCollege of Medicine, Pennsylvania State University, Hershey, PA.
Eduardo VilarDepartments of Clinical Cancer Prevention and GI Medical Oncology, UT MD Anderson Cancer Center, Houston, TX.
Ernest T HawkDivision of Cancer Prevention & Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX. ehawk@mdanderson.org slippman@ucsd.edu.
Cornell University · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
Mitochondrial and nuclear functions of NKX3.1 in regulating oxidative stress in prostate cancerR01CA233176 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ABATE-SHEN, CORY · 2019 to 2023
$1.9M
NCI NIH HHS P30 CA023100NCI NIH HHS R01 CA233176
6 · The paper itself

Abstract

The recent pace, extent, and impact of paradigm-changing cancer prevention science has been remarkable. The American Association for Cancer Research (AACR) convened a 3-day summit, aligned with five research priorities: (i) Precancer Atlas (PCA). (ii) Cancer interception. (iii) Obesity-cancer linkage, a global epidemic of chronic low-grade inflammation. (iv) Implementation science. (v) Cancer disparities. Aligned with these priorities, AACR co-led the Lancet Commission to formally endorse and accelerate the NCI Cancer Moonshot program, facilitating new global collaborative efforts in cancer control. The expanding scope of creative impact is perhaps most startling-from NCI-funded built environments to AACR Team Science Awarded studies of Asian cancer genomes informing global primary prevention policies; cell-free epigenetic marks identifying incipient neoplastic site; practice-changing genomic subclasses in myeloproliferative neoplasia (including germline variant tightly linked to JAK2 V617F haplotype); universal germline genetic testing for pancreatic cancer; and repurposing drugs targeting immune- and stem-cell signals (e.g., IL-1β, PD-1, RANK-L) to cancer interception. Microbiota-driven IL-17 can induce stemness and transformation in pancreatic precursors (identifying another repurposing opportunity). Notable progress also includes hosting an obesity special conference (connecting epidemiologic and molecular perspectives to inform cancer research and prevention strategies), co-leading concerted national implementation efforts in HPV vaccination, and charting the future elimination of cancer disparities by integrating new science tools, discoveries and perspectives into community-engaged research, including targeted counter attacks on e-cigarette ad exploitation of children, Hispanics and Blacks. Following this summit, two unprecedented funding initiatives were catalyzed to drive cancer prevention research: the NCI Cancer Moonshot (e.g., PCA and disparities); and the AACR-Stand Up To Cancer bold "Cancer Interception" initiative.

Indexed as

Biomedical ResearchCongresses as TopicHealth Plan ImplementationHealth Status DisparitiesHumansNeoplasmsObesityPrimary PreventionPublic HealthSocieties, MedicalSocieties, ScientificUnited States

Identifiers

PMID30530635
PMCPMC10344465
OpenAlexW2904452117

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.