Evidence map›Paper›PMID 30530620›Full record

ArticleInfection and immunity2019

A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal

Win-Yan Chan, Claire Entwisle, Giuseppe Ercoli, Elise Ramos-Sevillano, Ann McIlgorm, Paola Cecchini, Christopher Bailey, Oliver Lam, Gail Whiting, Nicola Green and 3 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. The Emergence of InvasiveFrontiers in microbiology · 2021
    Article
  16. Article
  17. New Strategy Is Needed to Prevent Pneumococcal Meningitis.The Pediatric infectious disease journal · 2020
    Article
  18. Panel 8: Vaccines and immunology.International journal of pediatric otorhinolaryngology · 2020
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Win-Yan ChanCentre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College Medical School Rayne Institute, London, United Kingdom.
Claire EntwisleImmunoBiology Ltd., Babraham, Cambridge, United Kingdom.
Giuseppe ErcoliCentre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College Medical School Rayne Institute, London, United Kingdom.
Elise Ramos-SevillanoCentre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College Medical School Rayne Institute, London, United Kingdom.
Ann McIlgormImmunoBiology Ltd., Babraham, Cambridge, United Kingdom.
Paola CecchiniImmunoBiology Ltd., Babraham, Cambridge, United Kingdom.
Christopher BaileyImmunoBiology Ltd., Babraham, Cambridge, United Kingdom.
Oliver LamNational Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, United Kingdom.
Gail WhitingNational Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, United Kingdom.
Nicola GreenUCL Great Ormond Street Institute of Child Health, London, United Kingdom.
David GoldblattUCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Jun X WheelerNational Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, United Kingdom.
Jeremy S BrownCentre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College Medical School Rayne Institute, London, United Kingdom jeremy.brown@ucl.ac.uk.
Babraham Institute · GBUniversity College London · GBNational Institute for Biological Standards and Control · GBGreat Ormond Street Hospital · GB

Funding

Department of HealthMedical Research Council MR/N02687X/1Medical Research Council MR/R001871/1Medical Research Council R/N02687X/1
6 · The paper itself

Abstract

Current vaccination against

Indexed as

AnimalsAntigens, BacterialMicePneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeAntigens, BacterialPneumococcal Vaccinesmultiple-antigen vaccineprotein antigenStreptococcus pneumoniaevaccines

Identifiers

PMID30530620
PMCPMC6386546
OpenAlexW2904099054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.