Evidence map›Paper›PMID 30530591›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

G2A Protects Mice against Sepsis by Modulating Kupffer Cell Activation: Cooperativity with Adenosine Receptor 2b.

Hong-Mei Li, Ji Hye Jang, Jun-Sub Jung, Jiseon Shin, Chul O Park, Yeon-Ja Kim, Won-Gyun Ahn, Ju-Suk Nam, Chang-Won Hong, Jongho Lee and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Hong-Mei LiDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.
Ji Hye JangDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.
Jun-Sub JungDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.
Jiseon ShinDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.ORCID 0000-0001-5389-611X
Chul O ParkDepartment of Biological Sciences, Seoul National University, Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.
Yeon-Ja KimDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.
Won-Gyun AhnDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.ORCID 0000-0002-9434-3543
Ju-Suk NamDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.
Chang-Won HongDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.ORCID 0000-0001-7745-9205
Jongho LeeDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea.
Yu-Jin JungDepartment of Biological Sciences, Kangwon National University, Chuncheon, Gangwon-do 24341, Republic of Korea.ORCID 0000-0002-4942-677X
Jiang-Fan ChenDepartment of Neurology, Boston University School of Medicine, Boston, MA 02118.
Katya RavidDepartments of Medicine and Biochemistry, Boston University School of Medicine, Boston, MA 02118.
H Thomas LeeDepartment of Anesthesiology, College of Physicians and Surgeons of Columbia University, New York, NY 10032; and.
Won-Ki HuhDepartment of Biological Sciences, Seoul National University, Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.ORCID 0000-0002-9091-6594
Janusz H KabarowskiDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294.
Dong-Keun SongDepartment of Pharmacology, Institute of Natural Medicine, College of Medicine, Hallym University, Chuncheon, Gangwon-do 24252, Republic of Korea; dksong@hallym.ac.kr.ORCID 0000-0002-9238-3816
Hallym University · KRBoston University · USSeoul National University · KRColumbia University · USKangwon National University · KRUniversity of Alabama at Birmingham · US

Funding

Paneth cells and acute kidney injuryR01DK109544 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LEE, H. THOMAS · 2017 to 2021
$1.8M
Peptidylarginine deiminase-4 and acute kidney injuryR01DK115694 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LEE, H. THOMAS · 2017 to 2021
$1.6M
NIDDK NIH HHS R01 DK109544NIDDK NIH HHS R01 DK115694
6 · The paper itself

Abstract

G2A is a GPCR abundantly expressed in immune cells. G2A

Indexed as

AnimalsAntibodies, BlockingCell Cycle ProteinsCells, CulturedCyclic AMPDisease Models, AnimalEscherichia coliEscherichia coli InfectionsHumansInterleukin-10Kupffer CellsMacrophages, PeritonealMaleMiceMice, Inbred C57BLMice, KnockoutAntibodies, BlockingCell Cycle ProteinsCyclic AMPG2A receptorInterleukin-10Reactive Oxygen SpeciesReceptor, Adenosine A2BReceptors, G-Protein-Coupled

Identifiers

PMID30530591
PMCPMC6477683
OpenAlexW2905004366

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.