ArticleSleep medicine2019
Sleep duration and risk of end-stage renal disease: the Singapore Chinese Health Study.
Article in Sleep medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The risk of chronic kidney disease or proteinuria with long or short sleep duration: a systematic review and meta-analysis of cohort studies.Clinical and experimental nephrology · 2025Pooled it
- Association between sleep duration from midlife and the risk of physical frailty in late life.Scientific reports · 2026Article
- Long nighttime sleep duration and risk of renal tubular damage: evidence from rural China and a Mendelian randomization analysis.Renal failure · 2025Observational
- Insomnia and sleep duration for kidney function: Mendelian randomization study.Renal failure · 2024Article
- Association between sleep duration from midlife to late life and the risk of depressive symptoms: the Singapore Chinese Health Study.BJPsych open · 2024Article
- The association of sleep duration with the risk of chronic kidney disease: a systematic review and meta-analysis.Clinical kidney journal · 2024Article
- Observational
- Sleep traits and risk of end-stage renal disease: a mendelian randomization study.BMC medical genomics · 2023Article
- Association of sleep characteristics with renal function in menopausal women without recognized chronic kidney disease.Frontiers in psychiatry · 2022Article
- Adherence to a Healthy Sleep Pattern and Risk of Chronic Kidney Disease: The UK Biobank Study.Mayo Clinic proceedings · 2022Article
- Functional outcomes of sleep predict cardiovascular intermediary outcomes and all-cause mortality in patients on incident hemodialysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Healthful dietary patterns and risk of end-stage kidney disease: the Singapore Chinese Health Study.The American journal of clinical nutrition · 2021Article
- Association of Sleep Duration With Atrial Fibrillation and Heart Failure: A Mendelian Randomization Analysis.Frontiers in genetics · 2021Article
- Pulse Pressure and the Risk of End-Stage Renal Disease Among Chinese Adults in Singapore: The Singapore Chinese Health Study.Journal of the American Heart Association · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesAlthough epidemiological evidence suggests that short sleep duration may affect renal function, the influence of long sleep and risk of end-stage renal disease (ESRD) is unclear. We examined the association between sleep duration and risk of ESRD.
methodsWe investigated sleep duration and ESRD risk in the Singapore Chinese Health Study, a prospective population-based cohort of 63,257 Chinese in Singapore, who were aged 45-74 years at recruitment (1993-1998). Information on daily sleep duration (including naps), diet, medical history and other lifestyle factors was collected at recruitment from in-person interviews. ESRD cases were identified via linkage with the nationwide Singapore Renal Registry through year 2014. We used the Cox proportional hazards regression method to estimate hazard ratio (HR) and 95% confidence interval (CI) of ESRD in relation to sleep duration.
resultsAfter an average 16.8 years of follow-up, 1143 (1.81%) ESRD cases were documented. Sleep duration had a U-shaped association with risk of ESRD (P for quadratic trend < 0.001). Compared with participants with 7 h/day of sleep, the multivariable adjusted HR (95% CI) of ESRD was 1.43 (1.18-1.74) for short sleep (≤5 h/day) and 1.28 (1.03-1.60) for long sleep duration (≥9 h/day). The increased risk was stronger in participants with more than 10 years of follow-up compared to those with shorter follow-up time, especially for long sleep (P for interaction = 0.003).
conclusionsOur findings demonstrated that both short and long sleep durations were associated with a higher risk of ESRD in this Asian population.
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