ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2019
Obesity and Weight Gain Since Early Adulthood Are Associated With a Lower Risk of Microscopic Colitis.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Factors for Microscopic Colitis: A Systematic Review and Meta-Analysis.Journal of gastroenterology and hepatology · 2025Pooled it
- Risk factors for immune checkpoint inhibitor colitis: a retrospective multi-center cohort study using electronic health records.Cancer immunology, immunotherapy : CII · 2026Article
- Autoimmune Thyroid Diseases and Microscopic Colitis: A Nationwide Matched Case-Control Study in Sweden.The Journal of clinical endocrinology and metabolism · 2025Article
- Update on the Epidemiology and Management of Microscopic Colitis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025Review
- The Gut Microbial Regulation of Epigenetic Modification from a Metabolic Perspective.International journal of molecular sciences · 2024Review
- A Literature Review of Microscopic Colitis.Cureus · 2024Review
- Microscopic Colitis and Risk of Incident Psoriasis: A Nationwide Population-Based Matched Cohort Study.Clinical epidemiology · 2024Article
- Adverse event profiles of microscopic colitis in the Japanese Adverse Drug Event Report (JADER) database.Scientific reports · 2022Article
- Alcohol Consumption is Associated With An Increased Risk of Microscopic Colitis: Results From 2 Prospective US Cohort Studies.Inflammatory bowel diseases · 2022Article
- Red meat consumption, obesity, and the risk of nonalcoholic fatty liver disease among women: Evidence from mediation analysis.Clinical nutrition (Edinburgh, Scotland) · 2022Article
- Obesity is associated with decreased risk of microscopic colitis in women.World journal of gastroenterology · 2022Article
- The Therapeutic Effect of SCFA-Mediated Regulation of the Intestinal Environment on Obesity.Frontiers in nutrition · 2022Review
- Gastrointestinal Infection and Risk of Microscopic Colitis: A Nationwide Case-Control Study in Sweden.Gastroenterology · 2021Article
- Weight gain during early adulthood, trajectory of body shape and the risk of nonalcoholic fatty liver disease: A prospective cohort study among women.Metabolism: clinical and experimental · 2020Article
- Progress in characterizing the linkage between Fusobacterium nucleatum and gastrointestinal cancer.Journal of gastroenterology · 2019Review
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Authors and funding
9 authors.
Funding
Abstract
BACKGROUND &
aimsObesity promotes intestinal inflammation and might contribute to the pathogenesis of inflammatory bowel disease. We examined the association between obesity and risk of microscopic colitis in a prospective cohort study.
methodsWe collected data from 192,101 women enrolled in the Nurses' Health Study (NHS) (from 1986 through 2014) or the NHSII (from 1991 through 2015). Anthropomorphic and lifestyle information were self-reported biennially. Obesity was defined using body mass index (BMI). Microscopic colitis was confirmed by review of medical records. We used Cox proportional hazard models to estimate adjusted hazard ratios (aHRs) and 95% CIs.
resultsAmong the participants in the NHS and NHSII, we confirmed 244 cases of microscopic colitis during 4,223,868 person-years of follow-up evaluation. Higher BMI was associated inversely with risk of microscopic colitis (Ptrend < .001). Compared with women with BMIs ranging from 18.5 to 20.9 kg/m
conclusionsUnlike many other immune- and metabolic-related disorders, obesity and weight gain since early adulthood were associated with a lower risk of microscopic colitis, based on an analysis of participants in the NHS and NHSII.
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