Evidence map›Paper›PMID 30529706›Full record

SynthesisJournal of the American Academy of Dermatology2019

Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions: A systematic review.

Cristian Navarrete-Dechent, Antonio P DeRosa, Caterina Longo, Konstantinos Liopyris, Margaret Oliviero, Harold Rabinovitz, Ashfaq A Marghoob, Allan C Halpern, Giovanni Pellacani, Alon Scope and 1 more

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Academy of Dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07277920 (Evaluation of Reflectance Confocal Microscopy), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07277920 recruitingnot on this mapstarted 2023, after this paper: background citation

Evaluation of Reflectance Confocal Microscopy (RCM) Features in Surgically Excised Atypical Melanocytic Lesions and Their Correlation With Next-Generation Sequencing (NGS) Patterns

TypeobservationalSponsorUniversity of Modena and Reggio EmiliaRan2023 to 2026Enrolled200ConditionsMelanocytic Nevi, Melanoma (Skin Cancer), Next Generation Sequencing (NGS)
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Probe-based confocal laser endomicroscopy for optical biopsy of basal cell carcinoma of the auricle.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Basosquamous carcinoma: Comprehensive epidemiological, clinical, dermoscopic, and confocal features from a single center institution.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  8. Article
  9. Review
  10. Comparison of reflectance confocal microscopy and line-field optical coherence tomography for the identification of keratinocyte skin tumours.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Article
  11. Article
  12. Observational
  13. Reflectance Confocal Microscopy of Aging Skin and Skin Cancer.Dermatology practical & conceptual · 2021
    Review
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cristian Navarrete-DechentDepartment of Dermatology, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Antonio P DeRosaSamuel J. Wood Library, Weill Cornell Medical College, New York, New York.
Caterina LongoDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy; Azienda Unità Sanitaria Locale, Istituto di Ricovero e Cura a Carattere Scientifico di Reggio Emilia, Centro Oncologico ad Alta Tecnologia Diagnostica-Dermatologia, Reggio Emilia, Italy.
Konstantinos LiopyrisDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Margaret OlivieroDermatology Associates, Plantation, Florida.
Harold RabinovitzDermatology Associates, Plantation, Florida.
Ashfaq A MarghoobDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Allan C HalpernDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Giovanni PellacaniDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
Alon ScopeDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Medical Screening Institute, Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Manu JainDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: jainm@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundThere is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs).

objectiveTo review published RCM terms for NMLs and identify likely synonymous terms.

methodsWe conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus-like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates.

resultsThe inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5% reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7%) versus 78 (74.2%) for BCC; 60 (64.5%) versus 33 (34.5%) for SCC, and 15 (45.4%) versus 18 (54.5%) for SK/SL/LPLK, respectively. LIMITATIONS: Articles that were not peer reviewed were excluded.

conclusionSystematic review of published RCM terms provides the basis for future NMLs terminology consensus.

Indexed as

Terminology as TopicBasal Cell CarcinomaCarcinoma, Squamous CellHumansKeratosis, SeborrheicLentigoMicroscopy, ConfocalSkin Neoplasmsactinic keratosisbasal cell carcinomadiagnosislichen planus-like keratosismelanomanonmelanoma skin cancerreflectance confocal microscopyseborrheic keratosissquamous cell carcinoma

Identifiers

PMID30529706
PMCPMC6830574

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.