Evidence map›Paper›PMID 30528980›Full record

ReviewNeuroscience letters2019

Review of diffusion MRI studies in chronic white matter diseases.

Rajikha Raja, Gary Rosenberg, Arvind Caprihan

Abstract readReview
In one paragraph

Review in Neuroscience letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Free water elimination tractometry for aging brains.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  9. Article
  10. Quantification of the in vivo brain ultrashort-TMagnetic resonance in medicine · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Advanced MRI in cerebral small vessel disease.International journal of stroke : official journal of the International Stroke Society · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rajikha RajaThe MIND Research Network, Albuquerque, NM, United States. Electronic address: rraja@mrn.org.
Gary RosenbergDepartment of Neurology, University of New Mexico Health Sciences Center, Albuquerque, NM, United States.
Arvind CaprihanThe MIND Research Network, Albuquerque, NM, United States.
Mind Research Network · USUniversity of New Mexico · US

Funding

MRI and CSF Biomarkers of White Matter Injury in VCIDUH3NS100598 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI ROSENBERG, GARY ALLEN · 2018 to 2020
$3.3M
NINDS NIH HHS UH3 NS100598
6 · The paper itself

Abstract

Diffusion MRI studies characterizing the changes in white matter (WM) due to vascular cognitive impairment, which includes all forms of small vessel disease are reviewed. We reviewed the usefulness of diffusion methods in discriminating the affected WM regions and its relation to cognitive impairment. These studies were categorized based on the diffusion MRI techniques used. The most common method was the diffusion tensor imaging, whereas other methods included diffusion weighted imaging, diffusion kurtosis imaging, intravoxel incoherent motion, and studies based on diffusion tractography. The diffusion measures showed correlation with cognitive scores and disease progression, with mean diffusivity being the most robust parameter. Future studies should focus on incorporating multi-compartment and higher order diffusion models, which can handle the presence of multiple and crossing fibers inside a voxel.

Indexed as

Diffusion Magnetic Resonance ImagingAnisotropyCerebral Small Vessel DiseasesChronic DiseaseCognitive DysfunctionDementia, VascularDiffusion Tensor ImagingHumansLeukoencephalopathiesCerebral small vessel diseasesDiffusion MRIMatter diseasesVascular cognitive imapairment and dementiaWhite

Identifiers

PMID30528980
PMCPMC6380179
OpenAlexW2903916188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.