ArticleJournal of biomechanics2019
Merged plantarflexor muscle activity is predictive of poor walking performance in post-stroke hemiparetic subjects.
Article in Journal of biomechanics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Flexible exoskeleton-assisted training enhances lower limb motor function after stroke: a systematic review and meta-analysis.Journal of neurology · 2025Pooled it
- The ReWalk ReStore™ soft robotic exosuit: a multi-site clinical trial of the safety, reliability, and feasibility of exosuit-augmented post-stroke gait rehabilitation.Journal of neuroengineering and rehabilitation · 2020Trial
- Heteronymous feedback from quadriceps onto soleus in stroke survivors.Journal of neuroengineering and rehabilitation · 2025Article
- Post-stroke Stiff-Knee gait: are there different types or different severity levels?Journal of neuroengineering and rehabilitation · 2025Article
- Heteronymous feedback from quadriceps onto soleus in stroke survivors.Research square · 2024Article
- Differences in kinetic factors affecting gait speed between lesion sides in patients with stroke.Frontiers in bioengineering and biotechnology · 2024Article
- The Effects of Stroke and Stroke Gait Rehabilitation on Behavioral and Neurophysiological Outcomes:: Challenges and Opportunities for Future Research.Delaware journal of public health · 2023Article
- Muscle synergies for evaluating upper limb in clinical applications: A systematic review.Heliyon · 2023Review
- Effects of soft robotic exoskeleton for gait training on clinical and biomechanical gait outcomes in patients with sub-acute stroke: a randomized controlled pilot study.Frontiers in neurology · 2023Article
- Muscle contributions to pre-swing biomechanical tasks influence swing leg mechanics in individuals post-stroke during walking.Journal of neuroengineering and rehabilitation · 2022Article
- Is modular control related to functional outcomes in individuals with knee osteoarthritis and following total knee arthroplasty?PloS one · 2022Article
- Is there frequency-specificity in the motor control of walking? The putative differential role of alpha and beta oscillations.Frontiers in systems neuroscience · 2022Review
- Training muscle activation patterns of the lower paretic extremity using directional exertion improves mobility in persons with hemiparesis: a pilot study.BMC biomedical engineering · 2021Article
- Intra-Subject and Inter-Subject Movement Variability Quantified with Muscle Synergies in Upper-Limb Reaching Movements.Biomimetics (Basel, Switzerland) · 2021Article
- Relationship between gait quality measures and modular neuromuscular control parameters in chronic post-stroke individuals.Journal of neuroengineering and rehabilitation · 2021Article
- Assessment of turning performance and muscle coordination in individuals post-stroke.Journal of biomechanics · 2021Article
- Effect of Walking Adaptability on an Uneven Surface by a Stepping Pattern on Walking Activity After Stroke.Frontiers in human neuroscience · 2021Article
- Effect of time window on MVC reference for quantifying spastic cocontraction in spastic paresis.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Stroke is the leading cause of long-term disability and individuals post-stroke often experience impaired walking ability. The plantarflexor (PF) muscles are critical to walking through their contributions to the ground reaction forces and body segment energetics. Previous studies have shown muscle activity during walking can be grouped into co-excited muscle sets, or modules. Improper co-activation, or merging of modules, is a common impairment in individuals post-stroke. The purpose of this study was to determine the influence of merged PF modules on walking performance in individuals post stroke by examining balance control, body support and propulsion, and walking symmetry. Muscle modules were identified using non-negative matrix factorization to classify subjects as having an independent or merged PF module. The merged group had decreased balance control with a significantly higher frontal plane whole-body angular momentum than both the independent and control groups, while the independent and control groups were not significantly different. The merged group also had higher paretic braking and nonparetic propulsion than both the independent and control groups. These results remained when comparisons were limited to subjects who had the same number of modules, indicating this was not a general effect due to subjects with merged PF having fewer modules. It is likely that a merged PF module is indicative of general PF dysfunction even when some activation occurs at the appropriate time. These results suggest an independent PF module is critical to walking performance, and thus obtaining an independent PF module should be a crucial aim of stroke rehabilitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.