Evidence map›Paper›PMID 30528365›Full record

ReviewPaediatric respiratory reviews2019

Question 3: Can we diagnose asthma in children under the age of 5 years?

C L Yang, J M Gaffin, D Radhakrishnan

Abstract readReview
In one paragraph

Review in Paediatric respiratory reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  14. Current Challenges in Pediatric Asthma.Children (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

C L YangDivision of Respiratory Medicine, British Columbia Children's Hospital, Vancouver, British Columbia, Canada. Electronic address: Connie.yang@cw.bc.ca.
J M GaffinDivision of Respiratory Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
D RadhakrishnanDepartment of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.

Funding

Indoor Air Quality and Respiratory Morbidity in School-Aged Children with Bronchopulmonary DysplasiaR01ES030100 · NIEHS · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2019 to 2023
$3.7M
School-based air pollution and asthma morbidity in Inner City School ChildrenK23AI106945 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2013 to 2017
$822k
NIAID NIH HHS K23 AI106945NIEHS NIH HHS R01 ES030100
6 · The paper itself

Abstract

The diagnosis of asthma in children under five years has been controversial due to changing concepts of what true asthma is in this age group. Previous diagnostic algorithms that used clinical indices to predict the persistence of asthma symptoms or phenotypes based on asthma triggers do not predict which children will benefit from asthma medication. A pragmatic approach to asthma diagnosis in this age group is based on identifying signs and symptoms of reversible airflow obstruction and documenting their response to asthma medication. Hopefully, this approach will provide clearer guidance to clinicians and improve asthma morbidity in these young children.

Indexed as

Respiratory SoundsAge FactorsAnti-Asthmatic AgentsAsthmaChild, PreschoolHumansInfantInflammationPhenotypeAnti-Asthmatic AgentsAsthmaChildDiagnosisInfantViral wheeze

Identifiers

PMID30528365
PMCPMC6444340

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.