Evidence map›Paper›PMID 30528056›Full record

ArticleFertility and sterility2019

Acute effects of air pollutants on spontaneous pregnancy loss: a case-crossover study.

Claire L Leiser, Heidi A Hanson, Kara Sawyer, Jacob Steenblik, Ragheed Al-Dulaimi, Troy Madsen, Karen Gibbins, James M Hotaling, Yetunde Oluseye Ibrahim, James A VanDerslice and 1 more

Open access · greenAbstract read
In one paragraph

Article in Fertility and sterility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Homo sapiens, industrialisation and the environmental mismatch hypothesis.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  3. Review
  4. Article
  5. Associations of climatic factors with pregnancy loss in Nicosia, Cyprus.Journal of exposure science & environmental epidemiology · 2025
    Article
  6. Article
  7. Article
  8. Obstetric care for environmental migrants.Irish journal of medical science · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Observable variations in human sex ratio at birth.PLoS computational biology · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Claire L LeiserPopulation Sciences, Huntsman Cancer Institute, Salt Lake City, Utah. Electronic address: claire.leiser@hci.utah.edu.
Heidi A HansonPopulation Sciences, Huntsman Cancer Institute, Salt Lake City, Utah; Department of Surgery, University of Utah, Salt Lake City, Utah.
Kara SawyerDivision of Emergency Medicine, University of Utah, Salt Lake City, Utah.
Jacob SteenblikDivision of Emergency Medicine, University of Utah, Salt Lake City, Utah.
Ragheed Al-DulaimiDepartment of Internal Medicine, Hurley Medical Center, Flint, Michigan; College of Human Medicine, Michigan State University, Lansing, Michigan.
Troy MadsenDivision of Emergency Medicine, University of Utah, Salt Lake City, Utah.
Karen GibbinsDepartment of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon.
James M HotalingDepartment of Surgery, University of Utah, Salt Lake City, Utah.
Yetunde Oluseye IbrahimDepartment of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah.
James A VanDersliceDepartment of Family and Preventive Medicine, University of Utah, Salt Lake City, Utah.
Matthew FullerDivision of Emergency Medicine, University of Utah, Salt Lake City, Utah.
University of Utah · USHuntsman Cancer Institute · USHurley Medical Center · USOregon Health & Science University · US

Funding

Utah Building Interdisciplinary Resreach Careers in Women's Health Career Development ProgramK12HD085852 · NICHD · UNIVERSITY OF UTAH · PI VARNER, MICHAEL W. · 2015 to 2019
$2.3M
NICHD NIH HHS K12 HD085852
6 · The paper itself

Abstract

objectiveTo investigate the relationship between acute exposure to air pollutants and spontaneous pregnancy loss.

designCase-crossover study from 2007 to 2015.

settingAn academic emergency department in the Wasatch Front area of Utah. PATIENT(S): A total of 1,398 women who experienced spontaneous pregnancy loss events. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Odds of spontaneous pregnancy loss. RESULT(S): We found that a 10-ppb increase in 7-day average levels of nitrogen dioxide was associated with a 16% increase in the odds of spontaneous pregnancy loss (odds ratio [OR] = 1.16; 95% confidence interval [CI] 1.01-1.33; P=.04). A 10-μg/m

conclusionsWe found that short-term exposure to elevated levels of air pollutants was associated with higher risk for spontaneous pregnancy loss.

Indexed as

Abortion, SpontaneousAdolescentAdultAir PollutantsCase-Control StudiesChildCross-Over StudiesEmergency Service, HospitalFemaleHumansInhalation ExposureMiddle AgedNitrogen DioxideParticle SizeParticulate MatterPregnancyAir PollutantsNitrogen DioxideParticulate Matteradverse pregnancy outcomesAir pollutionfemale reproductive effectsNO(2)PM(10)-PM(2.5)-ultrafine

Identifiers

PMID30528056
PMCPMC6351170
OpenAlexW2902054112

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.