Evidence map›Paper›PMID 30526879›Full record

ArticleCell stem cell2018

Does Adult Neurogenesis Persist in the Human Hippocampus?

Mercedes F Paredes, Shawn F Sorrells, Arantxa Cebrian-Silla, Kadellyn Sandoval, Dashi Qi, Kevin W Kelley, David James, Simone Mayer, Julia Chang, Kurtis I Auguste and 9 more

Abstract readLetterComment
In one paragraph

Article in Cell stem cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

  1. Review
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  7. Increasing adult-born neurons protects mice from epilepsy.bioRxiv : the preprint server for biology · 2024
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Mercedes F ParedesEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Shawn F SorrellsEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.
Arantxa Cebrian-SillaLaboratorio de Neurobiología Comparada, Instituto Cavanilles, Universidad de Valencia, CIBERNED, Valencia 46980, Spain.
Kadellyn SandovalEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Dashi QiState Key Laboratory of Medical Neurobiology and Institutes of Brain Science, Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Kevin W KelleyEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA.
David JamesEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA.
Simone MayerEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.
Julia ChangDavid Geffen School of Medicine, Department of Neurosurgery, Intellectual Development and Disabilities Research Center, University of California, Los Angeles, Los Angeles, CA, USA.
Kurtis I AugusteDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.
Edward F ChangDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.
Antonio J Gutierrez MartinUnidad de Cirugía de la Epilepsia, Hospital Universitario La Fe, Valencia 46026, Spain.
Arnold R KriegsteinEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Gary W MathernDepartments of Neurosurgery and Psychiatry & BioBehavioral Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Michael C OldhamEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Eric J HuangDepartment of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
Jose Manuel Garcia-VerdugoLaboratorio de Neurobiología Comparada, Instituto Cavanilles, Universidad de Valencia, CIBERNED, Valencia 46980, Spain.
Zhengang YangState Key Laboratory of Medical Neurobiology and Institutes of Brain Science, Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Arturo Alvarez-BuyllaEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: abuylla@stemcell.ucsf.edu.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 1985 to 2020
$29.6M
Regulation of Cellular Pathwaysin Human Brain DevelopmentP01NS083513 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FANCY, STEPHEN PHILIP JAMES · 2014 to 2024
$12.6M
NEUROGENESIS IN THE ADULT VERTEBRATE BRAINR01NS028478 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALVAREZ-BUYLLA, ARTURO · 1996 to 2024
$8.6M
CHARACTERIZATION OF NEURAL STEM CELLS IN THE ADULT BRAINR37NS028478 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALVAREZ-BUYLLA, ARTURO · 2000 to 2007
$2.9M
Late-migrating interneurons in the postnatal brainK08NS091537 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PAREDES, MERCEDES · 2015 to 2019
$968k
NIGMS NIH HHS T32 GM007618NINDS NIH HHS K08 NS091537NINDS NIH HHS P01 NS083513NINDS NIH HHS R01 NS028478NINDS NIH HHS R37 NS028478
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HippocampusNeurogenesisAdultHumans

Identifiers

PMID30526879
PMCPMC6800191

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.