The Exon Junction Complex: A Multitasking Guardian of the Transcriptome.

Calvin S Leung, Tracy L Johnson

Abstract readComment

In one paragraph

Article in Molecular cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it

0cells of the map it votes in

7citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

The exon junction complex is required for DMD gene splicing fidelity and myogenic differentiation.Cellular and molecular life sciences : CMLS · 2024
Article
The Exon Junction Complex Factor RBM8A in Glial Fibrillary Acid Protein-Expressing Astrocytes Modulates Locomotion Behaviors.Cells · 2024
Article
An RNAi screen of RNA helicases identifies eIF4A3 as a regulator of embryonic stem cell identity.Nucleic acids research · 2022
Article
Diverse Roles of the Exon Junction Complex Factors in the Cell Cycle, Cancer, and Neurodevelopmental Disorders-Potential for Therapeutic Targeting.International journal of molecular sciences · 2022
Review
The Physiological Roles of the Exon Junction Complex in Development and Diseases.Cells · 2022
Review
In-Depth Analysis Reveals Production of Circular RNAs from Non-Coding Sequences.Cells · 2020
Article
Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.Nucleic acids research · 2020
Article

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Calvin S LeungMolecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Tracy L JohnsonMolecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: tljohnson@ucla.edu.

Funding

UCLA NIGMS T32 Program AssessmentT32GM007185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TORRES, JORGE · 1985 to 2020

$21.7M

Eukaryotic RNA Processing and Chromatin ModificationR01GM085474 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOHNSON, TRACY L · 2010 to 2021

$2.6M

NIGMS NIH HHS R01 GM085474NIGMS NIH HHS T32 GM007185

6 · The paper itself

Abstract

In a recent issue of Molecular Cell, Boehm et al. (2018), Blazquez et al. (2018), and Gonatopoulos-Pournatzis et al. (2018) uncover novel mechanisms by which the cell regulates splicing of cryptic splice sites and microexons.

Indexed as

RNA Splice SitesTranscriptomeCell NucleusExonsRNA SplicingRNA Splice Sites

Identifiers

PMID30526869

DOI10.1016/j.molcel.2018.11.030

PMCPMC6823928

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.