ArticleAmerican journal of human genetics2018
The Genetic Ancestry of Modern Indus Valley Populations from Northwest India.
Article in American journal of human genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed.
- Analysis of whole exome sequencing in severe mental illness hints at selection of brain development and immune related genes.Scientific reports · 2021Trial
- Layers in the sand: The genetic imprint of migration, culture, and Indus craft in the Thar Desert.HGG advances · 2026Article
- Tracing the genetic legacy of Altaic-speaking populations suggested long-distance migration and multi-source admixture shape the genomic diversity of Xibe and Daur.Human genetics · 2026Article
- Northeast india: genetic inconsistency across ethnicity and geography.Molecular genetics and genomics : MGG · 2026Article
- Uncovering the Molecular Signatures of Rare Genetic Diseases in the Punjabi Population.International journal of molecular sciences · 2025Observational
- Investigating the demographic history of Sindhi population inhabited in West Coast India.Human genomics · 2025Article
- Population histories of the Indigenous Adivasi and Sinhalese from Sri Lanka using whole genomes.Current biology : CB · 2025Article
- Phylogenetic analysis of the enigmatic Kalash population in Pakistan.Scientific reports · 2025Article
- Tracing human genetic histories and natural selection with precise local ancestry inference.Nature communications · 2025Article
- Precision nutrition across climates: decoding diet, tradition, and genomic adaptations from South Asia to the Arctic.Frontiers in nutrition · 2025Review
- Ancestral origins and post-admixture adaptive evolution of highland Tajiks.National science review · 2024Article
- Ancestral Origins and Admixture History of Kazakhs.Molecular biology and evolution · 2024Article
- Human Y chromosome haplogroup L1-M22 traces Neolithic expansion in West Asia and supports the Elamite and Dravidian connection.iScience · 2024Article
- Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization.Circulation. Genomic and precision medicine · 2024Article
- Novel genetic association of the Furin gene polymorphism rs1981458 with COVID-19 severity among Indian populations.Scientific reports · 2024Article
- Populations of Latvia and Lithuania in the context of some Indo-European and non-Indo-European speaking populations of Europe and India: insights from genetic structure analysis.Frontiers in genetics · 2024Article
- Reconstructing the population history of the Sinhalese, the major ethnic group in Śrī Laṅkā.iScience · 2023Article
- A deep learning framework for characterization of genotype data.G3 (Bethesda, Md.) · 2022Article
- Contrasting maternal and paternal genetic histories among five ethnic groups from Khyber Pakhtunkhwa, Pakistan.Scientific reports · 2022Article
- Dissecting the genetic history of the Roman Catholic populations of West Coast India.Human genetics · 2021Article
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17 authors.
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Abstract
The Indus Valley has been the backdrop for several historic and prehistoric population movements between South Asia and West Eurasia. However, the genetic structure of present-day populations from Northwest India is poorly characterized. Here we report new genome-wide genotype data for 45 modern individuals from four Northwest Indian populations, including the Ror, whose long-term occupation of the region can be traced back to the early Vedic scriptures. Our results suggest that although the genetic architecture of most Northwest Indian populations fits well on the broader North-South Indian genetic cline, culturally distinct groups such as the Ror stand out by being genetically more akin to populations living west of India; such populations include prehistorical and early historical ancient individuals from the Swat Valley near the Indus Valley. We argue that this affinity is more likely a result of genetic continuity since the Bronze Age migrations from the Steppe Belt than a result of recent admixture. The observed patterns of genetic relationships both with modern and ancient West Eurasians suggest that the Ror can be used as a proxy for a population descended from the Ancestral North Indian (ANI) population. Collectively, our results show that the Indus Valley populations are characterized by considerable genetic heterogeneity that has persisted over thousands of years.
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