Evidence map›Paper›PMID 30526852›Full record

ArticleeLife2018

A repressor-decay timer for robust temporal patterning in embryonic

Inna Averbukh, Sen-Lin Lai, Chris Q Doe, Naama Barkai

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  11. Transcriptional regulation of neuronal identity.The European journal of neuroscience · 2022
    Review
  12. Review
  13. Review
  14. Article
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  16. Article
  17. Review
  18. Neural specification, targeting, and circuit formation during visual system assembly.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Integrated Patterning Programs DuringAnnual review of neuroscience · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Inna Averbukh *Department of Molecular Genetics, Weizmann institute of science, Rehovot, Israel.ORCID http://orcid.org/0000-0003-1863-205X
Sen-Lin Lai *Institute of Neuroscience, Institute of Molecular Biology, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.ORCID http://orcid.org/0000-0002-7531-283X
Chris Q DoeInstitute of Neuroscience, Institute of Molecular Biology, Howard Hughes Medical Institute, University of Oregon, Eugene, United States.ORCID https://orcid.org/0000-0001-5980-8029
Naama BarkaiDepartment of Molecular Genetics, Weizmann institute of science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-2444-6061
Howard Hughes Medical Institute · USWeizmann Institute of Science · IL

Funding

GENETIC AND MOLECULAR STUDIES OF NEUROGENESISR01HD027056 · NICHD · UNIVERSITY OF OREGON · PI Chris Q Doe · 1989 to 2026
$5.0M
Genetic and Molecular Studies of NeurogenesisR37HD027056 · NICHD · UNIVERSITY OF OREGON · PI DOE, CHRIS Q · 2012 to 2021
$3.0M
Howard Hughes Medical InstituteNICHD NIH HHS R01 HD027056NICHD NIH HHS R37 HD027056NIH HHS R01-HD27056
6 · The paper itself

Abstract

Biological timers synchronize patterning processes during embryonic development. In the

Indexed as

AnimalsBody PatterningCell DifferentiationCell LineageDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsEmbryo, NonmammalianGene DeletionGene Expression Regulation, DevelopmentalHomeodomain ProteinsNeural Stem CellsNeuronsPeriodicityPOU Domain FactorsSignal Transductioncas protein, DrosophilaDNA-Binding ProteinsDrosophila ProteinsHomeodomain Proteinsnub protein, DrosophilaPOU Domain FactorsTranscription Factorsbiological timercomputational biologydevelopmental biologyD. melanogasterneuroblastrobustnesssystems biology

Identifiers

PMID30526852
PMCPMC6303102
OpenAlexW2952297514

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.