Observational studyThe American journal of tropical medicine and hygiene2019
Clinical and Laboratory Characteristics of an Acute Chikungunya Outbreak in Bangladesh in 2017.
Observational study in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Events preceding death among chikungunya virus infected patients: a systematic review.Revista da Sociedade Brasileira de Medicina Tropical · 2020Pooled it
- Acute-phase clinical profile and quality of life in patients with chikungunya during the 2025 outbreak in Bangladesh: A facility-based cross-sectional study.PLoS neglected tropical diseases · 2026Article
- Clinical Features and Factors Associated with Disease Severity in Acute Chikungunya Fever: A Retrospective Analysis.Infection and drug resistance · 2026Article
- Seroprevalence of Dengue, Chikungunya, and Zika Viruses Among Febrile Patients in Dhaka, Bangladesh: A Hospital-Based Cross-Sectional Study.Pathogens (Basel, Switzerland) · 2025Article
- Acute Clinical Features and Persistence of Joint Pain in Probable Cases of Chikungunya Fever in Eritrea.Open access rheumatology : research and reviews · 2025Article
- Therapy for Chikungunya Arthritis: A Study of 133 Brazilian Patients.The American journal of tropical medicine and hygiene · 2023Article
- Distinguishing SARS-CoV-2 Infection and Non-SARS-CoV-2 Viral Infections in Adult Patients through Clinical Score Tools.Tropical medicine and infectious disease · 2023Article
- Prevalence, Risk Factors, and Prognosis of Liver Involvement in Adult Patients with Chikungunya in Thailand.The American journal of tropical medicine and hygiene · 2022Article
- Atypical skin manifestation in severe acute chikungunya infection in a pregnant woman: a case report.Journal of medical case reports · 2022Article
- Cardiomyopathy and Death Following Chikungunya Infection: An Increasingly Common Outcome.Tropical medicine and infectious disease · 2021Review
- Rheumatic manifestations of Chikungunya virus infection: Prevalence, patterns, and enthesitis.PloS one · 2021Article
- Cas13b-dependent and Cas13b-independent RNA knockdown of viral sequences in mosquito cells following guide RNA expression.Communications biology · 2020Article
- Cytokines and Chemokines in Chikungunya Virus Infection: Protection or Induction of Pathology.Pathogens (Basel, Switzerland) · 2020Review
- Mosquito-Borne Diseases Emergence/Resurgence and How to Effectively Control It Biologically.Pathogens (Basel, Switzerland) · 2020Review
- El Niño Southern Oscillation, overseas arrivals and imported chikungunya cases in Australia: A time series analysis.PLoS neglected tropical diseases · 2019Article
- Tropism of the Chikungunya Virus.Viruses · 2019Review
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11 authors.
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Abstract
From April to September 2017, Bangladesh experienced a huge outbreak of acute Chikungunya virus infection in Dhaka. This series describes the clinical and laboratory features of a large number of cases (690; 399 confirmed and 291 probable) suffered during that period. This observational study was carried out at Dhaka Medical College Hospital, Bangladesh. The median age of the patients at presentation was 38 years (IQR 30-50) with a male (57.3%) predominance. Hypertension and diabetes were the most common comorbidities. The mean (±SD) duration of fever was 3.7 (±1.4) days. Other common manifestations were arthralgia (99.2%), maculopapular rash (50.2%), morning stiffness (49.7%), joint swelling (48.5%), and headache (37.6%). Cases were confirmed by anti-chikungunya IgG (173; 43.3%), IgM (165; 42.3%), and reverse transcription polymerase chain reaction (44; 11.0%). Important laboratory findings include high erythrocyte sedimentation rate (156; 22.6%), raised serum glutamic pyruvic transaminase (73; 10.5%), random blood sugar (54; 7.8%), leukopenia (72; 10.4%), thrombocytopenia (41; 5.9%), and others. The oligo-articular (453; 66.1%) variety of joint involvement was significantly more common compared with the poly-articular (237; 34.5%) variety. Commonly involved joints were the wrist (371; 54.1%), small joints of the hand (321; 46.8%), ankle (251; 36.6%), knee (240; 35.0%), and elbow (228; 33.2%). Eleven cases were found to be complicated with neurological involvement and two of them died. Another patient died due to myocarditis. Public health experts, clinicians, and policymakers could use the results of this study to construct the future strategy tackling chikungunya in Bangladesh and other epidemic countries.
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