Evidence map›Paper›PMID 30526742›Full record

Trial reportThe American journal of tropical medicine and hygiene2019

Maternal Influenza Vaccination and the Risk of Laboratory-Confirmed Influenza Among Household Contacts Under the Age of Five in Mali.

Andrea G Buchwald, Boubou Tamboura, Fadima C Haidara, Flanon Coulibaly, Moussa Doumbia, Fatoumata Diallo, Sarah Boudova, Adama M Keita, Samba O Sow, Karen Kotloff and 2 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Household Overcrowding in Iran, a Low-middle-income Country: How Major of a Public Health Concern Is It?Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Andrea G BuchwaldCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland.
Boubou TambouraCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Fadima C HaidaraCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Flanon CoulibalyCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Moussa DoumbiaCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Fatoumata DialloCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Sarah BoudovaCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland.
Adama M KeitaCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Samba O SowCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Karen KotloffCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland.
Myron LevineCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland.
Milagritos D TapiaCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland.
Centre Pour le Développement des Vaccins-Mali · MLUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza transmission is increased among household contacts. Vaccination decreases transmission; however it is unclear how vaccinating a single individual alters disease risk among household contacts, particularly in regions with low vaccination coverage. Pregnant women were randomized to influenza or control vaccination. Households were visited weekly until infants born to enrolled women reached 6 months. Household contacts younger than 5 years were tested for laboratory-confirmed influenza (LCI). Incidence of LCI and rate ratios (RtR) comparing incidence between vaccine groups were calculated. The secondary infection rate (SIR) was calculated for households where LCI was detected. The H1N1 strain in the vaccine was a match for circulating H1N1 during the study, thus, all analyses were performed for H1N1-LCI and any LCI. A total of 5,345 household contacts younger than 5 years followed for a mean of 228 days (standard deviation [SD] = 45 days) experienced 2,957 influenza-like illness episodes. Incidence of any LCI and H1N1-LCI was 23 (

Indexed as

AdultChild, PreschoolFamilyFemaleHumansIncidenceInfantInfluenza A Virus, H1N1 SubtypeInfluenza, HumanInfluenza VaccinesMaleMaliMothersPregnancyRisk FactorsVaccinationInfluenza Vaccines

Identifiers

PMID30526742
PMCPMC6335916
OpenAlexW2903100635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.