Evidence map›Paper›PMID 30526636›Full record

ReviewItalian journal of pediatrics2018

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children.

Carlo Caffarelli, Fabrizio Franceschini, Davide Caimmi, Francesca Mori, Lucia Diaferio, Dora Di Mauro, Carla Mastrorilli, Stefania Arasi, Simona Barni, Paolo Bottau and 10 more

Abstract readReviewConsensus Statement
In one paragraph

Review in Italian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Review
  4. Review
  5. Don't we overestimate drug allergies in children?International journal of occupational medicine and environmental health · 2023
    Article
  6. Review
  7. Review
  8. Hypersensitivity to Intravenous Iron Preparations.Children (Basel, Switzerland) · 2022
    Review
  9. Review
  10. Review
  11. When toothache results in asthma diagnosis.International journal of occupational medicine and environmental health · 2022
    Article
  12. Review
  13. Review
  14. Drug Allergy in children: focus on beta-lactams and NSAIDs.Acta bio-medica : Atenei Parmensis · 2020
    Article
  15. Review
  16. Review
  17. Review
  18. Drug-induced anaphylaxis in children.Acta bio-medica : Atenei Parmensis · 2019
    Review
  19. Pediatric drug hypersensitivity: which diagnostic tests?Acta bio-medica : Atenei Parmensis · 2019
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Carlo CaffarelliClinica Pediatrica, Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43122, Parma, Italy. carlo.caffarelli@gmail.com.
Fabrizio FranceschiniPediatric Unit, "G. Salesi" Children Hospital, Ancona, Italy.
Davide CaimmiAllergy Unit, Departement de Pneumologie et Addictologie, Hôpital Arnaud de Villeneuve, CHRU de Montpellier, Montpellier, France.
Francesca MoriAllergy Unit, Department of Pediatric, Anna Meyer Children's University Hospital, Florence, Italy.
Lucia DiaferioDepartment of Paediatrics, Aldo Moro University of Bari-Giovanni XXIII Hospital, Bari, Italy.
Dora Di MauroClinica Pediatrica, Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43122, Parma, Italy.
Carla MastrorilliClinica Pediatrica, Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43122, Parma, Italy.
Stefania ArasiPediatric Allergy Unit, Bambino Gesù Academic Hospital, Rome, Vatican State, Italy.
Simona BarniAllergy Unit, Department of Pediatric, Anna Meyer Children's University Hospital, Florence, Italy.
Paolo BottauDepartment of Paediatrics and Neonatology, Ospedale di Imola, Azienda USL, Imola, Italy.
Silvia CaimmiPediatric Clinic, Department of Pediatrics, University of Pavia, Pavia, Italy.
Fabio CardinaleDepartment of Pediatrics, Pediatric Hospital "Giovanni XXIII", University of Bari, Bari, Italy.
Pasquale ComberiatiPediatric Clinic, Department of Life and Reproduction Sciences, University of Verona, Verona, Italy.
Giuseppe CrisafulliAllergy Unit, Department of Pediatrics, University of Messina, Messina, Italy.
Lucia LiottiPediatric Unit, Civic Hospital, Senigallia, Italy.
Umberto PelosiPediatric Unit, Santa Barbara Hospital, Iglesias, Italy.
Francesca SarettaPediatric Unit, Palmanova Hospital, Palmanova, Italy.
Gianluigi MarsegliaPediatric Clinic, University of Pavia, IRCCS Policlinico "S. Matteo" Foundation, Pavia, Italy.
Marzia DuseDepartment of Pediatrics, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Francesco ParavatiPediatric Unit, Infant Maternal Department, Azienda Sanitaria Provinciale Crotone, Crotone, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs). Laboratory tests for identifying children who are allergic to drugs have low diagnostic accuracy and predictive value. The gold standard to diagnose DHR is represented by the drug provocation test (DPT), that aims of ascertaining the causative role of an allergen and evaluating the tolerance to the suspected drug. Different protocols through the administration of divided increasing doses have been postulated according to the type of drug and the onset of the reaction (immediate or non immediate reactions). DPT protocols differ in doses and time interval between doses. In this position paper, the Italian Pediatric Society for Allergy and Immunology provides a practical guide for provocation test to antibiotics and NSAIDs in children and adolescents.

Indexed as

Anti-Bacterial AgentsAnti-Inflammatory Agents, Non-SteroidalChildDrug HypersensitivityHumansAnti-Bacterial AgentsAnti-Inflammatory Agents, Non-SteroidalAllergyAntibioticsChallengeChildrenDiagnosisDrug allergyDrug hypersensitivity reactionsNon-steroidal anti-inflammatory drugsPediatric

Identifiers

PMID30526636
PMCPMC6286516

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.