Evidence map›Paper›PMID 30526606›Full record

ArticleAnnals of clinical microbiology and antimicrobials2018

Adherent/invasive Escherichia coli (AIEC) isolates from asymptomatic people: new E. coli ST131 O25:H4/H30-Rx virotypes.

Edwin Barrios-Villa, Gerardo Cortés-Cortés, Patricia Lozano-Zaraín, Margarita María de la Paz Arenas-Hernández, Claudia Fabiola Martínez de la Peña, Ygnacio Martínez-Laguna, Carmen Torres, Rosa Del Carmen Rocha-Gracia

Abstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Resistance phenotype and virulence potential ofMicrobiology (Reading, England) · 2024
    Article
  5. Article
  6. Article
  7. Genomic Characterization of UropathogenicInternational journal of molecular sciences · 2023
    Article
  8. Strain belonging to an emerging, virulent sublineage of ST131Frontiers in cellular and infection microbiology · 2023
    Article
  9. Characterization of DiarreaghenicAntibiotics (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Antimicrobial Resistance Profiles of Adherent InvasiveAntibiotics (Basel, Switzerland) · 2020
    Article
  14. Frontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Edwin Barrios-VillaBenemérita Universidad Autónoma de Puebla, Posgrado en Ciencias Microbiológicas, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Puebla, Mexico.
Gerardo Cortés-CortésBenemérita Universidad Autónoma de Puebla, Posgrado en Ciencias Microbiológicas, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Puebla, Mexico.
Patricia Lozano-ZaraínBenemérita Universidad Autónoma de Puebla, Posgrado en Ciencias Microbiológicas, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Puebla, Mexico.
Margarita María de la Paz Arenas-HernándezBenemérita Universidad Autónoma de Puebla, Posgrado en Ciencias Microbiológicas, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Puebla, Mexico.
Claudia Fabiola Martínez de la PeñaBenemérita Universidad Autónoma de Puebla, Posgrado en Ciencias Microbiológicas, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Puebla, Mexico.
Ygnacio Martínez-LagunaBenemérita Universidad Autónoma de Puebla, Posgrado en Ciencias Microbiológicas, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Puebla, Mexico.
Carmen TorresÁrea de Bioquímica y Biología Molecular, Universidad de La Rioja, Logroño, Spain.
Rosa Del Carmen Rocha-GraciaBenemérita Universidad Autónoma de Puebla, Posgrado en Ciencias Microbiológicas, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Puebla, Mexico. rochagra@yahoo.com.

Funding

Consejo Nacional de Ciencia y Tecnología 178942Consejo Nacional de Ciencia y Tecnología 233611Consejo Nacional de Ciencia y Tecnología 411957Vicerrectoría de Investigación y Estudios de Posgrado, BUAP ARHM/NAT/17Vicerrectoría de Investigación y Estudios de Posgrado, BUAP ROGR/NAT17-G
6 · The paper itself

Abstract

backgroundThe widespread Escherichia coli clone ST131 implicated in multidrug-resistant infections has been recently reported, the majority belonging to O25:H4 serotype and classified into five main virotypes in accordance with the virulence genes carried.

methodsPathogenicity Islands I and II (PAI-I and PAI-II) were determined using conventional PCR protocols from a set of four E. coli CTX

findingsNon-reported virulence patterns were found in our isolates, two of them carried satA, papA, papGII genes and the two-remaining isolates carried cnfI, iroN, satA, papA, papGII genes, and none of them belonged to classical ST131 virotypes, suggesting an endemic distribution of virulence genes and two new virotypes. The presence of PAI-I and PAI-II of Uropathogenic E. coli was determined in three of the four strains, furthermore adherence and invasion assays demonstrated higher degrees of attachment/invasion compared with the control strains. We also amplified intI1, insA and insB genes in all four samples.

interpretationThe results indicate that these strains own non-reported virotypes suggesting endemic distribution of virulence genes, our four strains also belong to an AIEC pathotype, being this the first report of AIEC in México and the association of AIEC with healthy donors.

Indexed as

Bacterial AdhesionAsymptomatic DiseasesEscherichia coli ProteinsFecesHumansSerogroupUropathogenic Escherichia coliVirulenceEscherichia coli ProteinsAIECCrohn’s diseaseIBDVirotype

Identifiers

PMID30526606
PMCPMC6287351

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.