ArticleBMC public health2018
Decline in HPV-vaccination uptake in Denmark - the association between HPV-related media coverage and HPV-vaccination.
Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
79 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effects of human papillomavirus (HPV) vaccination programmes on community rates of HPV-related disease and harms from vaccination.The Cochrane database of systematic reviews · 2025Pooled it
- Human papillomavirus (HPV) vaccination for the prevention of cervical cancer and other HPV-related diseases: a network meta-analysis.The Cochrane database of systematic reviews · 2025Pooled it
- Parental vaccine refusal, non-vaccinated children, and outbreaks of Vaccine-Preventable Diseases (VPDs) in Europe: a systematic review of aetiology and risk.BMC public health · 2025Pooled it
- Trial
- The Effect of a Web-Based Cervical Cancer Survivor's Story on Parents' Behavior and Willingness to Consider Human Papillomavirus Vaccination for Daughters: Randomized Controlled Trial.JMIR public health and surveillance · 2022Trial
- Hepatitis A virus knowledge and immunization attitudes and practices in the United Arab Emirates community.Scientific reports · 2021Trial
- How the unvaccinated have been portrayed in the urban English-language Canadian popular press since the declared end of the COVID-19 pandemic emergency.Human vaccines & immunotherapeutics · 2026Article
- Interplay between vaccine-related informational milestones, social media discourse, and vaccine administration rates for human papillomavirus and measles/mumps/rubella vaccines in the United States.Human vaccines & immunotherapeutics · 2026Article
- Mapping the global research landscape on HPV vaccine hesitancy: a machine-learning based bibliometric analysis.Virology journal · 2026Article
- A Questionnaire Survey on Human Papillomavirus Vaccination Among Hospital-Based Healthcare Professionals.Yonago acta medica · 2026Article
- Marginalized voices on HPV vaccination in India: exploring knowledge, attitudes, and acceptance.Frontiers in global women's health · 2026Article
- Adverse events following HPV vaccine reported to the Vaccine Adverse Event Reporting System.PloS one · 2026Article
- A content analysis of religion and HPV vaccine news coverage in Canada.Human vaccines & immunotherapeutics · 2025Article
- Knowledge, attitudes, and practices regarding HPV infection, cervical cancer, and HPV vaccination among Emirati women.Future oncology (London, England) · 2025Article
- The credibility struggle of mRNA vaccine rumors: A communication model to understand the impact of skepticism on public perception.Journal of public health research · 2025Article
- Development of an intervention to increase HPV vaccine uptake in Colombia.Pilot and feasibility studies · 2025Article
- Menstrual Cycle Length Changes Following Vaccination Against Influenza Alone or With COVID-19.JAMA network open · 2025Article
- Cohort profile: The BiCoVac cohort - a nationwide Danish cohort to assess short and long-term symptoms following COVID-19 vaccination.European journal of epidemiology · 2025Article
- Determinants of high vaccine confidence and uptake among the Australian public: insights from a cross-sectional study.Frontiers in public health · 2025Article
- Infectious disease hospitalization after receipt of human papillomavirus vaccine: a nationwide register-based cohort study among Danish, Finnish, Norwegian, and Swedish girls.European journal of epidemiology · 2025Article
19 more citing papers are in PubMed but not listed here.
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6 authors.
Funding
Abstract
backgroundIn 2014, Denmark experienced a rapid decline in vaccination uptake for the human papillomavirus (HPV) vaccine after a successful introduction of the vaccine in 2009. Before the decline, the uptake of the first HPV vaccine was around 90% for girls born in the period 1998 to 2000, while it dropped to 54% for girls born in 2003. The decline followed negative public attention from 2013 coinciding with increasing suspected adverse-event reporting to the Danish Medicines Agency. The aim of this study is to describe the HPV-vaccination uptake, to quantify relevant HPV-related media coverage, and analyse the relation between media coverage and HPV-vaccination acceptance in Denmark in year 2009-2016.
methodsThree types of data were used for the analysis: Immunisation data from 243,415 girls, media coverage (8524 news items) and Google search activity. We used changes in the correlation between media coverage and vaccination uptake to identify a changing point in their relationship. The relationship before and after the changing point was analysed determined on the interactions between vaccination uptake, media and search activity, with search activity as a proxy for public attention.
resultsWe identified July 2013 as a changing point in the relationship between media coverage and vaccination uptake. We found no significant relationship between media coverage and vaccination uptake in the first part of the time series (June 2009 to June 2013), whereas from July 2013 and onwards there was a negative Pearson's correlation of - 0.52. The changing point coincides with both an increase in Google searches for "HPV side effects" and media coverage with negative content.
conclusionsFollowing a successful launch of the HPV-vaccination programme, concerns about vaccine safety shifted the public opinion and the coverage by the media. The noticeable shift in correlation between vaccination uptake and media coverage before and after July 2013 could indicate that increased media coverage influenced the decline in vaccination uptake. Media monitoring may represent an important tool in future monitoring and assessment of confidence in vaccination programmes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.