Evidence map›Paper›PMID 30526281›Full record

ArticleJournal of neurotrauma2021

Influence of Antiplatelet and Anticoagulant Drug Use on Outcomes after Chronic Subdural Hematoma Drainage.

Michael T C Poon, Catherine Rea, Angelos G Kolias, Paul M Brennan, British Neurosurgical Trainee Research Collaborative (BNTRC)

Abstract readMulticenter Study
In one paragraph

Article in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  11. REPLY.AJNR. American journal of neuroradiology · 2023
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  14. Chronic Subdural Hematoma.Deutsches Arzteblatt international · 2022
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Michael T C PoonDepartment of Clinical Neuroscience, Western General Hospital, Edinburgh, United Kingdom.
Catherine ReaDepartment of Haematology, Eastbourne District General Hospital, Eastbourne, United Kingdom.
Angelos G KoliasDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge and Addenbrooke's Hospital, Cambridge, United Kingdom.
Paul M BrennanDepartment of Clinical Neuroscience, Western General Hospital, Edinburgh, United Kingdom.
British Neurosurgical Trainee Research Collaborative (BNTRC)

Funding

Department of Health 12/35/57Department of Health HTA/13/15/02Department of Health II-C5-0715-20005Department of Health NIHR-RP-R3-12-013Medical Research Council G0502030Medical Research Council G0600986Medical Research Council G0601025Medical Research Council G1002277Medical Research Council G9439390Medical Research Council MR/L010305/1
6 · The paper itself

Abstract

We aim to describe the outcomes after chronic subdural hematoma drainage (CSDH) management in a large cohort of patients on antithrombotic drugs, either antiplatelets or anticoagulants, at presentation and to inform clinical decision making on the timing of surgery and recommencement of these drugs. We used data from a previous UK-based multi-center, prospective cohort study. Outcomes included recurrence within 60 days, functional outcome at discharge, and thromboembolic event during hospital stay. We performed Cox regression on recurrence and multiple logistic regression on functional outcome. There were 817 patients included in the analysis, of which 353 (43.2%) were on an antithrombotic drug at presentation. We observed a gradual reduction in risk of recurrence for patients during the 6 weeks post-CSDH surgery. Neither antiplatelet nor anticoagulant drug use influenced risk of CSDH recurrence (hazard ratio, 0.93; 95% confidence interval [CI], 0.58-1.48;

Indexed as

AgedAged, 80 and overAnticoagulantsCohort StudiesDrainageFemaleHematoma, Subdural, ChronicHumansMaleMiddle AgedPlatelet Aggregation InhibitorsPostoperative ComplicationsPreoperative CareProspective StudiesRisk FactorsTreatment OutcomeAnticoagulantsPlatelet Aggregation Inhibitorsanticoagulantantiplateletchronic subdural hematomafunctional outcomerecurrence

Identifiers

PMID30526281
PMCPMC8060161

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.